Pathnologic @pathnologic
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Path Geek - All things #pathology
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Herpes Simplex Virus 
Lymphadenitis 
 • Expanded paracortex 
 • HSV-infected cells are 
present in areas
• HSV-infected cells ... Lymphadenitis #HSV #Pathology ... #Microscopy #Clinical ... #LymphNode
Hobnail variant of PTC: micropapillary architecture, dense eosinophilic cytoplasm, hobnail cells with apical nuclei, and marked
Hobnail variant ... cytoplasm, hobnail cells ... PTC #Papillary #Thyroid ... #Carcinoma #Pathology ... #Clinical #Microscopy
The many faces of the Hodgkin/Reed-Sternberg (HRS) cell: Even as medical students we are aware of
Reed-Sternberg cell ... (RS cell). ... Many variants exist ... #Pathology #Clinical ... #Microscopy
Oncocytic Variant of Medullary Carcinoma
Don't assume every oncocytic thyroid tumor is a Hurthle cell neoplasm! Nested
Oncocytic Variant ... every oncocytic thyroid ... tumor is a Hurthle cell ... Medullary #Carcinoma #Pathology ... #Microscopy #Clinical
Paracoccidioides brasiliensis Lymphadenitis: 

Paracoccidioidomycosis is a systemic fungal infection rare in the US, but endemic in
fibrosis (A) and well-formed ... seen within giant cells ... Lymphadenitis #Pathology ... #LymphNode #Clinical ... #Microscopy
Diffuse Sclerosis Variant—PTC 
 - Rare variant of PTC 
 - Approximately 3% ofall PTC
Diffuse Sclerosis ... • Carcinoma cells ... PTC #Papillary #Thyroid ... #Cancer #Pathology ... Clinical #Gross #Microscopy
Signet ring cell histiocytes in lymph node sinuses! This can mimic metastatic adenocarcinoma. Histiocytes have ingested
Signet ring cell ... #SignetRing #Cell ... #Histiocytes #LymphNode ... #Pathology #Clinical ... #Microscopy
A morphologic mosaic of NUT carcinoma: monotonous primitive cells, basophilic to clear cytoplasm, abrupt keratinization, prominent
monotonous primitive cells ... -NUT fusion or variants ... NUT #carcinoma #Pathology ... #Clinical #Microscopy
Amiodarone induced thyroid changes

Histopath: Remarkably enlarged follicles, distended with colloid, without 
scalloping, and lined by flattened
Amiodarone induced thyroid ... flattened follicular cells ... change, Follicular cells ... thyrotoxicosis #AIT #Pathology ... #Clinical #Microscopy
Squamous-Cell Carcinoma of the Tongue - Intraoral examination revealed a well-circumscribed superficial ulcer, with a homogeneous
Squamous-Cell Carcinoma ... red and white patch ... invasive squamous-cell ... B) #Clinical #Pathology ... Tongue #Squamous #Microscopy