Algorithms in Medicine @MatthewHoMD
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Matthew Ho, MD PhD https://twitter.com/MatthewHoMD
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diagnosis differential hematology workup testing aiha anemias asthma autoimmune celiac copd deficiency disease ferritin function gastroenterology hemolysis hypokalemia interpretation iron
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Hemolytic Anemias ... Differential Diagnosis Algorithm ... Signs of anemia ... Anemias (AIHAs) ... #Diagnosis #Algorithm
Laboratory Testing in Hemolytic Anemia Intravascular vs Extravascular Hemolysis Reticulocytes Unconjugated bilirubin LDH Peripheral smear Haptoglobin Urine hemosiderin Urine hemoglobin Carboxyhemoglobin #Hemolytic #Anemia #Laboratory #Testing #workup
Laboratory Testing in Hemolytic ... Anemia Intravascular ... Extravascular Hemolysis ... Carboxyhemoglobin #Hemolytic ... #Anemia #Laboratory
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach ... to Anemia - Differential ... -100): • Non-hemolytic ... , CKD • Hemolytic ... #MCV #Algorithm
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table Warm AIHA (48-70%) Cold AHA (16-32%) • Donath-Landsteiner HA (paroxysmal
Autoimmune Hemolytic ... Anemia (AIHA) - ... #Autoimmune #Hemolytic ... #Anemia #AIHA #
Iron Deficiency Anemia - Differential Diagnosis Algorithm Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR • Blood loss:
Iron Deficiency Anemia ... Differential Diagnosis Algorithm ... extravascular) hemolysis ... Iron #Deficiency #Anemia ... Differential #Diagnosis #Algorithm
Approach to Hypoproliferative Macrocytic Anemia • 812, Folate Deficiency • MDS+ • Hypothyroid • Liver Disease
Hypoproliferative Macrocytic Anemia ... #Macrocytic #Anemia ... differential #diagnosis #algorithm
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Differential Diagnosis Algorithm ... blood loss, Acute hemolysis ... , deficiency anemia ... Differential #Diagnosis #Algorithm
Approach to Leukocytosis - Differential Diagnosis Algorithm Features of hematologic malignancy: • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
Differential Diagnosis Algorithm ... hepatomegaly • Labs: anemia ... Differential #Diagnosis #Algorithm
Pulmonary Function Testing (PFT) Interpretation Algorithm Restrictive Lung Disease: • Chest wall or neuromuscular disorders • Interstitial
Interpretation Algorithm ... Lung Disease Obstructive ... Interpretation #Algorithm
Hypokalemia - Differential Diagnosis Algorithm Transcellular Shift: • Alkalosis • ↑ beta-2 adrenergic simulation • Erythropoiesis
Differential Diagnosis Algorithm ... in pernicious anemia ... Differential #Diagnosis #Algorithm
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