Algorithms in Medicine @MatthewHoMD
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Matthew Ho, MD PhD https://twitter.com/MatthewHoMD
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Hypoxemia Differential Diagnosis Algorithm by A-a Gradient

Normal A-a Gradient:
 • ↓ Atmospheric pressure
 • Hypoventilation: CNS
Hypoxemia Differential ... Diagnosis Algorithm ... by A-a Gradient ... Hypoxemia #Hypoxia #Differential ... #Diagnosis #Algorithm
Ascites Differential Diagnosis Table - Serum Ascites Albumin Gradient (SAAG)

SAAG ≥ 1.1:
 • Cirrhosis
 • Portal
Ascites Differential ... Diagnosis Table ... Ascites Albumin Gradient ... tamponade • IVC obstruction ... #Diagnosis #Table
Thrombocytopenia - Differential Diagnosis Algorithm

Decreased production:
 • Bone marrow suppression
 • Bone marrow failure
 • Bone
Thrombocytopenia - Differential ... Diagnosis Algorithm ... Thrombocytopenia #Differential ... #Diagnosis #Algorithm ... #hematology #platelets
Pulmonary Function Testing (PFT) Interpretation Algorithm

Restrictive Lung Disease:
 • Chest wall or neuromuscular disorders
 • Interstitial
Pulmonary Function ... Interpretation Algorithm ... Lung Disease Obstructive ... #Pulmonary #Function ... #diagnosis #asthma
Approach to Leukocytosis - Differential Diagnosis Algorithm

Features of hematologic malignancy:
 • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
Leukocytosis - Differential ... Diagnosis Algorithm ... anemia, ↑ MCV, ↑/↓ platelets ... #Leukocytosis #Differential ... #Diagnosis #Algorithm
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Thrombocytosis - Elevated Platelet ... Count - Differential ... Diagnosis Algorithm ... #Differential # ... Diagnosis #Algorithm
Pancytopenia - Differential Diagnosis Algorithm
 • 12-13 g/dL,
 • ANC < 1800/uL,
 • platelet < 150,000/uL

Initial
Pancytopenia - Differential ... Diagnosis Algorithm ... < 1800/uL, • platelet ... Diagnosis: • ... #Diagnosis #Algorithm
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
Diagnosis and Management ... Algorithm Suspected ... hemosiderin, Hepatic function ... #Diagnosis #Management ... #Algorithm #hematology
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Hypokalemia - Differential ... Diagnosis Algorithm ... GI losses (NG suction ... #Hypokalemia #Differential ... #Diagnosis #Algorithm
Algorithm for Suspected SVC Syndrome

SVC syndrome suspected: Facial/arm/neck edema, distended neck/chest veins, facial plethora, dyspnea, cough,
Algorithm for Suspected ... SVC Syndrome Grading ... head or neck with functional ... SVC #Syndrome #Algorithm ... #diagnosis #management