38 results
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... of Systemic Lupus ... Butterfly rash, Vasculitis ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Diagnosis of IgA Vasculitis (Henoch-Schönlein Purpura) - French Vasculitis Study Group 

1) Suggestive clinical manifestations
1) Suggestive clinical ... - Most common systemic ... individuals - Clinical ... the skin - Systemic ... HSP #Diagnosis #Rheumatology
Dermatological semiology of Cutaneous Vasculitis 

Clinicopathologic correlations
 • Purpura, papules, pustules, necrosis: involvement of small vessels
Infections (1-2% ... #dermpath #dermatology ... #semiology #signs ... lesions #diagnosis #clinical ... pathology #lesions #differential
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential ... purpura: strong sign ... ) - 2 relevant ... differential #diagnosis ... #rheumatology #
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
• Blood smear: Differential ... spherocytosis 2) ... FOR a cause → Systematic ... diagnosis #management #treatment ... #rheumatology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... Significance (MGUS) - Differential ... Monoclonal #Gammopathy #Clinical ... #Diagnosis #hematology ... #oncology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
inflammatory vasculitis ... Diagnosis = clinical ... very remarkable w/differential ... Treatment of GCA ... them, but urgent rheumatology
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
weakness, less systemic ... , holster sign, ... weakness after 2 ... years of treatment ... Myositis #diagnosis #rheumatology
Cutaneous manifestations associated with myelodysplastic syndrome
 • Myeloid hemopathy with the most frequent skin lesions (20%)
manifestations +++ 2. ... leukocytoclastic vasculitis ... myelodysplastic #syndrome #differential ... #diagnosis #dermatology ... #oncology #clinical
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... Damage Through 2 ... Cryoglobulinemia) - 2. ... Syndrome: • Clinical ... classification #rheumatology