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diagnosis differential nephrology acute ain ana anca antibodies antibody antineutrophil antinuclear bloodsmear borrelia clinical diseases injury interstitial kidney kidneyinjury management
Guide to Acute Kidney Injury (AKI) What to ask/look for: - HPI, PMH, full ROS
- Urinalysis/microscopy ... rhabdo/TLS) Causes ... Atheroemboli — 1% #AcuteKidneyInjury ... #Diagnosis #Algorithm ... #Causes #Differential
Algorithmic Approach to Acute Interstitial Nephritis When to suspect AIN? (not sensitive) • AKI, AKD, rapidly progressive
Algorithmic Approach ... sensitive) • AKI ... sterile pyuria, WBC casts ... eosinophiluria, microscopic ... proteinuria, granular casts
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm Acute Kidney Injury (AKI) - Acute increase
Causes of Acute ... • Hepatorenal syndromes ... Epithelial cell casts ... Obstruction • Cast ... polyangiitis /microscopic
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Workup Algorithm ... dipstick, urine microscopy ... osmolarity If cause ... • Cardio-renal syndrome ... #Workup #Algorithm
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... Differential Diagnosis Algorithm ... • Fanconi's syndrome ... sediment - WBC/RBC casts ... polyangiitis (GPA) / microscopic
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
polyangiitis), MPA (microscopic ... EGPA) • Renal: (AKI ... Goodpasture's cause ... FINDINGS: • U/A: microscopic ... hematuria, RBC casts
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Anti-dsDNA (in 70% of cases ... seen in 30—70% of cases ... • Sjögren syndrome ... Vasculitis: • Microscopic ... polyangiitis - PR3
Borrelia recurrentis on Peripheral Blood Smear 23M Somali refugee recently arrived w/severe abd pain, confusion and fever
resolved after 2-3d ... Northeast Africa with cases ... Several cases have ... Syndrome: 3d of ... recurrentis #BloodSmear #microscopy
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