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diagnosis nephrology differential acute aki nephrotic urine ain blood chronic ckd comparison glomerular hematuria injury interpretation kidney kidneydisease kidneyinjury microscopy
Algorithmic Approach to Acute Interstitial Nephritis When to suspect AIN? (not sensitive) • AKI, AKD, rapidly progressive
sterile pyuria, WBC casts ... eosinophiluria, microscopic ... , mild tubular proteinuria ... , granular casts ... #nephrology #diagnosis
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... Differential Diagnosis Algorithm ... • Fanconi's syndrome ... sediment - WBC/RBC casts ... polyangiitis (GPA) / microscopic
Nephritic vs Nephrotic Syndrome Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes. Step
Nephritic vs Nephrotic Syndrome ... hematuria and/or proteinuria ... hematuria (RBC casts ... #Comparison #Algorithm ... #Nephrology #Diagnosis
Urine Microscopy - Casts Acellular Casts • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... suggestive of nephrotic sydnrome ... suggestive of interstitial ... #Urine #Microscopy ... #nephrology #interpretation
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm Acute Kidney Injury (AKI) - Acute increase
• Hepatorenal syndromes ... Epithelial cell casts ... Obstruction • Cast ... polyangiitis /microscopic ... polyangiitis) Acute Interstitial
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
disease - Alport syndrome ... pain hematuria syndrome ... hematuria: - RBC casts ... Brown urine - Proteinuria ... #urology #nephrology
Causes of Chronic Kidney Disease - Differential Diagnosis Algorithm Decreased kidney function (eGFR < 60 ml/min/1.73 m2)
Differential Diagnosis Algorithm ... Glomerular (Proteinuria ... Hypertension Interstitial ... Sterile pyuria, WBC casts ... #Causes
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Injury - AKI Workup Algorithm ... dipstick, urine microscopy ... osmolarity If cause ... renal biopsy • Interstitial ... #causes
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Algorithm - Approach ... hemolytic-uremic syndrome ... cell/white cell casts ... #nephrotic #syndrome ... #nephrology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
• Hematuria, proteinuria ... affects the skin, neurologic ... (PR3-ANCA)): Microscopic ... tract, and often causes ... inflammatory lesions - interstitial
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