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diagnosis causes management treatment classification hemolytic activetb chronic disease latenttb mcv reticulocyte rheumatology tb tuberculosis abscess adultonset agglutinin anemias arteritis
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Hemolytic Anemias ... - Differential ... Hypersplenism, Infection ... #Anemias #Differential ... #hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Volume (MCV) - Differential ... Diagnosis Algorithm ... Inflammation • Cancer ... #Differential # ... #Causes #Hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach ... to Anemia - Differential ... Macroangiopathic, Infections ... Reticulocytosis, MDS ... Diagnosis #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
- Differential ... Diagnosis Algorithm ... circulation - Infections ... anemia • ... #Causes #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... Diagnosis Algorithm ... blood loss, Acute hemolysis ... , deficiency anemia ... Malignancy: Metastatic cancer
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
deficiency • Fanconi’s anemia ... telomeropathy Cancer ... Antibody-mediated hemolysis ... deficiency Infections ... #Diagnosis #Hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
infiltration (e.g. cancer ... , infection), Marrow ... Microangiopathic hemolytic ... Production #Index #hematology ... #anemia #differential
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Volume (MCV) - Differential ... Diagnosis Algorithm ... • Bleeding • Hemolysis ... Inflammation, Chronic Infection ... #Causes #Hematology
Causes of Hemoptysis - Differential Diagnosis Algorithm Massive Hemoptysis (>I00 mL in 24 hours) • Malignancy •
- Differential ... Diagnosis Algorithm ... Malformation Normal CXR ... Vasculitis Infection ... #Differential #
Chronic Cough - Differential Diagnosis Algorithm Red Flags: • Fever, night sweats, chills (infection) • Weight loss,
Chronic Cough - Differential ... Diagnosis Algorithm ... sweats, chills (infection ... disease or CHF) • Hemoptysis ... ) • Abnormal CXR
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