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Approach to Hypoproliferative Macrocytic Anemia • 812, Folate Deficiency • MDS+ • Hypothyroid • Liver Disease
Deficiency • MDS ... Hypothyroid • Liver Disease ... #Macrocytic #Anemia ... #differential #diagnosis ... #algorithm #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... disorders • Celiac disease ... effect following treatment ... Iron deficiency anemia ... #Hematology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Illness Script Signs ... Diagnosis: • Pancytopenia ... Treatment: • Consider ... Can progress to MDS ... #treatment #hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... - Differential Diagnosis ... #Differential #Diagnosis ... #Algorithm #Causes ... #Hematology
Common RBC Inclusions and Associations • Howell Jolly Bodies: Hyposplenism, Asplenism, Severe hemolytic anemia • Heinz
, Hemolytic anemia ... : Hemoglobin H disease ... , Sickle cell, MDS ... Inclusions #Bodies #diagnosis ... #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... cytopenias (usually anemia ... only curative treatment ... Myelodysplastic #Syndrome #MDS ... #treatment #hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Iron deficiency anemia ... anemia (sometimes ... , MDS, Chemotherapy ... #differential #diagnosis ... #hematology #microscopy
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
- Differential Diagnosis ... Non-megaloblastic: Liver disease ... Reticulocytosis, MDS ... #Differential #Diagnosis ... #hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Diagnostic Framework ... chronic kidney disease ... Alcohol use, Liver disease ... #differential #diagnosis ... #causes #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... - Differential Diagnosis ... • Liver Disease ... #Algorithm #Causes ... #Hematology
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