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diagnosis rheumatology symptoms causes algorithm hematology erythematosus lupus neurology sle systemic cardiology dermatology gastroenterology headache oncology pericarditis vasculitis activation adultonset
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
myocarditis, coronary arteritis ... SLE, Reactive arthritis ... Ocular melanoma • Arthritis ... SLE, Reactive Arthritis ... Recurrent and chronic arthritis-Azathioprine
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
thromboembolic disease ... Abnormalities: macrocytic anemia ... (MDS) Most met ... (MDS) and/or ... • giant cell arteritis
Suspected Celiac Disease - Diagnosis Algorithm Celiac disease suspected: • Signs and symptoms of celiac disease •
suspected: • Signs ... Iron-deficiency anemia ... unresponsive to treatment ... microscopic colitis Differential ... , eosinophilic enteritis
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm No Objective Weakness • Cardio-pulmonary disease
Cardio-pulmonary disease ... • Anemia • ... Deconditioning • Arthritis ... • Endocrine Disease ... Lambert-Eaton Myasthenic Syndrome
Causes of Pericardial Effusion - Differential Diagnosis Infectious: • Viral: Enterovirus, Herpesvirus, Adenovirus, Parvovirus • Bacterial: Mycobacterium
Pericardial Effusion - Differential ... SLE, Rheumatoid Arthritis ... : EGPA, Horton Disease ... , Takayasu Disease ... • Metabolic: Uremia
Behcet's Syndrome - Treatment Ulcers: • Treatment: Topical steroids • Prevention: Colchicine • Azathioprine for refractory disease Arthritis:
Behcet's Syndrome ... : • Treatment: ... Arthritis: • Colchicine ... #Syndrome #Treatment ... #management #pharmacology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... Fever, Arthralgia/arthritis ... fraction < 20% Differential ... #diagnosis #management ... #treatment #rheumatology
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Causes of Fatigue - Differential ... Hematologic • Anemia ... • Rheumatoid Arthritis ... Obstructive Pulmonary Disease ... Chronic Fatigue Syndrome
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
of hip (rare), Arthritis ... Demyelinating syndromes ... pain (20%) Renal disease ... ) Blood (75%): Anemia ... erythematosus #signs
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Manifestations: - Arthritis ... - Hemolytic anemia ... (aPL) 30-45% Differential ... sclerosis, Still's disease ... autoantibodies #signs
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