52 results
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Aplastic Anemia ... Illness Script Signs ... Treatment: • Consider ... Can progress to MDS ... diagnosis #management #treatment
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
, Chronic disease ... anemia (sometimes ... Liver Disease, MDS ... myeloma Rouleaux: Chronic ... Multiple myeloma, Chronic
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... myelodysplastic syndrome (MDS ... Hypocellular/Hypoplastic MDS ... abnormalities typical for MDS ... Treatment:
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Polycythemia Vera • Chronic ... : • Acute or Chronic ... effect following treatment ... Iron deficiency anemia
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
cytopenias (usually anemia ... only curative treatment ... Myelodysplastic #Syndrome #MDS ... Diagnosis #Management #treatment
Risk Factors and Signs of Copper Deficiency
Risk Factors:
 • Gastrointestinal: Previous upper bowel resection/bariatric surgery, Inflammatory
Risk Factors and Signs ... bowel disease, Chronic ... dental fixatives, Treatment ... , Malnutrition Signs ... Haematological: Anaemia
Suspected Celiac Disease - Diagnosis Algorithm

Celiac disease suspected:
 • Signs and symptoms of celiac disease
 •
suspected: • Signs ... Iron-deficiency anemia ... unresponsive to treatment ... discernable cause • Signs
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
of exposure to HDS ... Hidden OTC and HDS ... treatments Search ... dechallenge • Acute or chronic ... e.g. ascites), Chronic
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Chronic Lymphocytic ... 5) Symptoms of anemia ... transformation) Treatment ... marrow failure with anemia ... uw_IMresidency #CLL #Chronic
Korsakoff Syndrome
Clinical Findings:
 • Confabulation: Usually initial phase of the disease
 • Anterograde amnesia: Memory impairment
• Anterograde amnesia ... Chronic presentation ... Encephalopathy Treatment