11 results
Hormonal Regulation of the Blood Calcium concentration

#Calcium #Regulation #Parathyroid #Calcitonin #Calcitriol #PTH #Endocrinology #Pathophysiology #Hormones
#Parathyroid #Calcitonin ... #Calcitriol #PTH
Impact and Challenges With Vitamin D to Treat Secondary Hyperparathyroidism in Patients With Chronic Kidney Disease
Calcitriol ... - Suppresses SHPT ... or better than calcitriol ... or better than calcitriol ... Cholecalciferol #Calcitriol
Multiple Endocrine Neoplasias (MEN syndromes) 

MEN I
• Hyperparathyroidism 
• Hypercalcemia 
• Possible ZE syndrome 
• Various
• Increased calcitonin ... • Increased calcitonin ... MultipleEndocrineNeoplasia #Differential
Hypercalcemia - Differential Diagnosis Algorithm
Elevated PTH (High or normal):
 • Primary Hyperparathyroidism
 • Familial Hypocalciuric Hypercalcemia
Low
Hypercalcemia - Differential ... PTH: • Elevated Calcitriol ... Hypercalcemia #Differential
Hypophosphatemia Diagnostic Algorithm
- GI Losses
- Redistribution
- 1° HPT
- 1° Renal PO4 wasting: Hereditary, TIO, Fanconi Syndrome,
Redistribution - 1° HPT ... diagnosis #Algorithm #differential
Workup of Hypercalcemia - Differential Diagnosis Algorithm
High or Normal PTH:
 • Hyperparathyroidism: Parathyroid adenoma, Parathyroid hyperplasia,
Hypercalcemia - Differential ... diseases, Idiopathic calcitriol ... Hypercalcemia #Differential
Hypercalcemia - Differential Diagnosis Algorithm
Primary Hyperparathyroidism
 • Adenoma
 • Hyperplasia
 • MEN 1 and 2A
Tertiary Hyperparathyroidism
Hypercalcemia - Differential ... Excess Vitamin D/Calcitriol ... Hypercalcemia #Differential
Causes of Hypercalcemia
Parathyroid gland structure-related
 • Primary hyperparathyroidism
 • Parathyroid adenoma
 • Parathyroid hyperplasia
 • Parathyroid
prostate (release of calcitriol ... endocrinology #diagnosis #differential
Hypercalcemia - Hormones and Pathophysiology  
Calcitriol:
 • Bones: Enhances mineralization
 • GI Tract: ↑ Ca2+
Pathophysiology Calcitriol ... Ca2+, ↓ PO4- Calcitonin
Pharmacologic Options for Hypercalcemia Associated with Cancer
Rehydration with NS followed by loop diuretics
 • IV normal
conversion to calcitriol ... • Calcitonin