3616 results
Uric Acid Homeostasis
In the liver, purines are metabolized to uric acid. The last step in purine
Uric Acid Homeostasis ... metabolized to uric acid ... converts uric acid ... Homeostasis #Gout #Pathophysiology ... #Medications #Management
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... fetal free fatty acid ... Intermediate fatty acid ... obgyn #diagnosis #management ... #pathophysiology
Alkaptonuria (Black Urine Disease)
Urine turns dark when left standing due to oxidation of homogentisic acid 
Clinical
of homogentisic acid ... intervertebral discs Management ... Pediatrics #Diagnosis #Pathophysiology
Intracranial Hemorrhage (ICH) and Increased Intracranial Pressure (ICP) - Pathophysiology
ICH Management:
1. Manage Blood Pressure
  •
Pressure (ICP) - Pathophysiology ... ICH Management ... and via lactic acid ... Pressure #ICP #Pathophysiology ... #neurosurgery #management
Chemical Eye Injury: Pathogenesis and clinical findings
Exogenous chemical to the eye and/or adnexa
 • Ammonia, sodium
and hydrochloric acid ... the most common acids ... EMERGENCY: immediate management ... following initial management ... #opthalmology #pathophysiology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Lysis Syndrome: • Pathophysiology ... Elevated uric acid ... TLS #diagnosis #management
Pathways Involved in Protein and Amino Acid Metabolism in Chronic Kidney Disease. The tricarboxylic acid (TCA)
Protein and Amino Acid ... tricarboxylic acid ... metabolize amino acids ... products of amino acid ... #Pathophysiology
Hyperuricemia: Pathogenesis and Complications

 - Hypercalcemia (due to diseases like Sarcoidosis and Hyperparathyroidism) -> Accumulation of
to filter uric acid ... like lactic acid ... and keto-acids) ... secretion of uric acid ... Hyperuricemia #Pathophysiology
Gastric Acid Secretion - Pathophysiology
Chief cell - Pepsinogen
Parietal cell - Acid, Intrinsic factor
G cell - Gastrin
Inhibitors:
Gastric Acid Secretion ... - Pathophysiology ... Parietal cell - Acid ... Somatostatin Phases of acid ... #Secretion #Pathophysiology
Mechanism of Action of Bile Acid Sequestrants
Bile Acid Sequestrants → ↓ Hepatic Bile Acid Pool →
Action of Bile Acid ... Sequestrants Bile Acid ... ↓ Hepatic Bile Acid ... ↑ Hepatic Bile Acid ... sequestration #pathophysiology