9 results
Nephron Pathophysiology - Diuretic Sites of Action
Diuretics
1) Acetazolamide/canagliflozin
2) Osmotic agents (mannitol, urearetics)
3) Loop agents (eg, furosemide)
4)
Nephron Pathophysiology ... Loop agents (eg, furosemide ... Adenosine #Nephron #Pathophysiology ... Sites #Action #nephrology ... #pharmacology
Pharmacokinetics of commonly used diuretics medications in CKD, Cirrhotic Ascites, and Heart Failure
 • Furosemide
 •
Heart Failure • Furosemide ... Spironolactone MCW Nephrology ... #diuretics #pharmacology ... halflife #comparison #table
Summary of Diuretic Agents 
Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction
CARBONIC ANHYDRASE
DIURETICS • Furosemide ... #Medications #Pharmacology ... #summary #table ... #nephrology
Diuretics - Pharmacology

Thiazides diuretics:
 • Inhibit Na+ Cl- cotransporter in distal tubule
 • Chlorothiazide, Chlorthalidone, Indapamide,
Diuretics - Pharmacology ... • Bumetanide, Furosemide ... the nephron by excretion ... -promote water excretion ... #nephrology #conversion
Furosemide (Lasix) Pharmacology
 • IV Furosemide in Acute Heart Failure
 • Causes of Diuretic Resistance
 •
Furosemide (Lasix ... ) Pharmacology ... • IV Furosemide ... #Lasix #Pharmacology ... #nephrology #pathophysiology
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
straight segments - Secretion ... coupled to K+and H+ secretion ... Segments #Function #Pathophysiology ... #Tubules #Table ... #Pharmacology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Regulating Renal Excretion ... Ethacrynic acid, Furosemide ... #Diuresis #Nephrology ... #Pharmacology # ... Medications #Table
Pharmacologic Options for Hypercalcemia Associated with Cancer
Rehydration with NS followed by loop diuretics
 • IV normal
Pharmacologic Options ... GFR and renal excretion ... of Ca2+ • Furosemide ... drugs #treatment #pharmacology ... #table
Adrenoceptor Actions
α1
 • Vascular smooth muscle - Contraction
 • Genitourinary smooth muscle - Contraction
 • Intestinal
ß-cells - ↓ Insulin secretion ... cells - ↑ Renin secretion ... receptors #actions #pharmacology ... #pathophysiology ... #comparison #table