69 results
Pathophysiology of Tumor Lysis Syndrome (TLS)
Tumor Cell Lysis
-> Release of DNA
 • Purines -> Hypoxanthine /
Pathophysiology ... of Tumor Lysis Syndrome ... (TLS) Tumor Cell ... • Hyperkalemia ... #TLS #Pathophysiology
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
Classification of Tumor ... Lysis Syndrome ... : • Hypovolemia ... hydroxide • Hyperkalemia ... #TumorLysis #Syndrome
Tumor lysis syndrome refers to the constellation of metabolic disturbances that occurs when large numbers of
Tumor lysis syndrome ... hyperuricemia, #hyperkalemia ... hyperphosphatemia, #hypocalcemia ... acutekidneyinjury #Pathophysiology ... #Presentation #TLS
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Renin secreting tumor ... , Gitelman syndrom ... @priti899 #Hypokalemia ... potassium #low #nephrology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
Causes of Hypokalemia ... Clinicians should also ... Renin-secreting tumor ... #hypokalemia ... algorithm #causes #nephrology
Causes of HyperKalemia - Differential Diagnosis
Increased extracellular K+:
 • Tissue injury
 • Hemolysis
 • Rhabdomyolysis
 •
Causes of HyperKalemia ... Rhabdomyolysis • Tumor ... lysis syndrome ... blockers - MCW Nephrology ... MCW_Nephrology #HyperKalemia
Hypokalemia Differential Diagnosis Algorithm
Hypertensive:
 • High Al, Low R - Primary aldosteronism
 • High Al, High
Hypokalemia Differential ... Renin-secreting tumor ... acid, Liddle's Syndrome ... #Hypokalemia # ... Diagnosis #Algorithm #nephrology
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects
 • Serotonin Syndrome:
   - Autonomic Hyperactivity:
• Serotonin Syndrome ... Ocular Clonus, Tremor ... - Nausea - Tremor ... Serotonin #Inhibitors #Pathophysiology ... #Pharmacology #
Tumor lysis syndrome (TLS) - Pathophysiology:
→ Massive tumor cell lysis
→ Release of large amounts of K+,
Tumor lysis syndrome ... (TLS) - Pathophysiology ... : → Massive tumor ... #TumorLysis #syndrome ... #TLS #Pathophysiology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Lysis Syndrome ... Leukostasis: • Pathophysiology ... hyperviscosity syndrome ... • Pathophysiology ... hydration - Hyperkalemia