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diagnosis management barre cancer differential emergencies guillain nephrology oncologic rheumatology tumor aki apml calcium cerebritis classification cns cppd deposition dermatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
: - Neuro: AMS ... , AKI, acute limb ... Syndrome: • Pathophysiology ... #Syndrome #TLS ... diagnosis #management #hematology
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS Laboratory TLS: • Uric
Classification of Tumor Lysis ... Syndrome (TLS) ... • AKI (defined as ... #TumorLysis #Syndrome ... #management #oncology
Tumor Lysis Syndrome An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... An acute, life-threatening ... grade lymphoma & Acute ... #Syndrome #TLS ... #oncology #management
Acute Kidney Injury (AKI) in Patients with Cancer Cancer Related • Hypercalcemia • Intravenous contrast •
Acute Kidney Injury ... change disease • Hematologic ... malignancies Treatment ... Interleukin-2) • Tumor lysis ... #AKI #Cancer #Oncology
Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
Diagnosis Framework HEMATOLOGIC ... Hyperviscosity Syndrome ... of breath • Neurologic ... EMERGENCIES: Tumor Lysis ... Hyperuricemia • Acute
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Pathophysiology ... diagnosis #management #hematology ... #oncology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
antibiotics TLS ... (tumor-lysis syndrome ... ): - Hematologic ... low Ca - q8 h TLS ... : - Seen with AML
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
thyroid, Sjogren syndrome ... proximal weakness, arms ... Generalized fatigue - ALS ... aspiration and acute ... diagnosis #management #neurology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Acute febrile ... , breast CA - Hematologic ... Treatment: - Systemic ... #diagnosis #dermatology ... #oncology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Disease, PRES Pathophysiology ... (for secondary APS ... Erythematosus #SLE #CNS #neurology ... #rheumatology #
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