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Antiphospholipid Syndrome (APS) APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
) APS is a rare ... Antiphospholipid antibodies (aPL ... 1 of the three aPLs ... diagnosed with APS ... recommended in APS
Recurrent / Breakthrough DVT During Anticoagulation Subtherapeutic Anticoagulation Hypercoagulable State - Antithrombin deficiency - Hypercoagulability ot
Behcet's disease - APLS
Antiphospholipid Syndrome (Hughes' Syndrome) Antiphospholipid syndrome - an autoimmune condition where the affected individual produces antibodies
Hughes #Syndrome #APLS
Causes of Purpura - Differential Diagnosis Non-PalpabIe → Palpable • Thrombocytopenia (HIT, ITP/HUS), Coagulation defects (DIC, warfarin
Vasculopathy - HyperC: APLS
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
• Catastrophic APLS
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Incidence: common in APL ... unless severe APLS
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Hyperviscosity, TTP, APLS ... Antiphospholipid antibodies (APLS
A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
promyelocytic leukemia (APL ... In addition to APL ... Rods #AuerRods #APL
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 Auer Rods - Bone marrow aspiration revealed 5% blasts and 65% promyelocytes; many promyelocytes had prominent
Clinical #Path #APL
Raynaud Phenomenon Differential Diagnosis: Rheumatologic - MCC systemic sclerosis, RA, SLE, Sjogren syndrome, Antisynthetase syndrome, MCTD Heme -
Hypercoagulable state (eg APLA
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