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differential algorithm management causes clinical cardiology radiology pocus pulmonary table signs comparison symptoms neurology classification pathophysiology peds hematology nephrology syndrome
Antiphospholipid Syndrome (APS) APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
Antiphospholipid antibodies (aPL ... antibodies is unknown Diagnosis ... 1 of the three aPLs ... patients to be diagnosed ... #diagnosis #management
Antiphospholipid Syndrome (Hughes' Syndrome) Antiphospholipid syndrome - an autoimmune condition where the affected individual produces antibodies
Hughes #Syndrome #APLS ... Signs #Symptoms #Diagnosis
Causes of Purpura - Differential Diagnosis Non-PalpabIe → Palpable • Thrombocytopenia (HIT, ITP/HUS), Coagulation defects (DIC, warfarin
- Differential Diagnosis ... Vasculopathy - HyperC: APLS ... #Differential #Diagnosis
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
Differential diagnosis ... • Catastrophic APLS ... #differential #diagnosis
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Incidence: common in APL ... opacities • Diagnosis ... • Differential Diagnosis ... unless severe APLS ... Syndrome #APML #diagnosis
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
- Differential Diagnosis ... Hyperviscosity, TTP, APLS ... Antiphospholipid antibodies (APLS ... #differential #diagnosis
Raynaud Phenomenon Differential Diagnosis: Rheumatologic - MCC systemic sclerosis, RA, SLE, Sjogren syndrome, Antisynthetase syndrome, MCTD Heme -
Phenomenon Differential Diagnosis ... Hypercoagulable state (eg APLA ... - Frostbite #Diagnosis
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
- Differential Diagnosis ... SLE • CLL • APLA ... #Differential #Diagnosis
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Erythematosus - Diagnosis ... Anti-cardiolipin (aPL ... - Anti-B2GP1 (aPL ... Differential Diagnosis ... Erythematosus #Diagnosis
A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
She was diagnosed ... promyelocytic leukemia (APL ... In addition to APL ... Rods #AuerRods #APL
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