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pocus cardiology echocardiogram diagnosis hematology ultrasound coagulation psax management pericardial differential effusion endocarditis aortic cardiac causes dic disseminated intravascular laboratory
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal PT ... Prothrombin Time (PT ... typically prolong PT ... antibody Prolonged PT ... #Abnormal #PT
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
for a Prolonged PT ... and aPTT If the ... PT and the aPTT ... #Abnormal #PT ... #aPTT #Prolonged
Prothrombin Time (PT) and Partial Thromboplastin Time (PTT) Prothrombin Time (PT) - Often Elevated in: • Vitamin
Prothrombin Time (PT ... Prothrombin Time (PT ... • Factor XI, IX ... elevated in: • DIC ... thematttsai #PT
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Prolonged PT ... /PTT • Low plasma ... organ damage Clinical ... Fibrinogen: ↓ • PT ... INR < 2.3 - APTT
Aortic and Mitral Valve Vegetations in Endocarditis on POCUS - PLAX Why would this 30 y/o male
Endocarditis on POCUS - PLAX ... Pt subsequently ... went to OR to fix ... Endocarditis #POCUS #PLAX ... #clinical #cardiology
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 Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
== NORMAL PT ... level NORMAL PT ... If the PT remains ... ABNORMAL PT/ ... of the PT and the
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC) Platelet count: • Expected: Low (or normal) • Elevation
Intravascular Coagulation (DIC ... platelet aggregation PT ... , aPTT: • Expected ... using INR use PT ... small vessels #DIC
Von Willebrand Disease - Most common inherited bleeding disorder Clinical • Easy bruising •
bleeding disorder Clinical ... 2B) • Normal PT ... INR • Normal aPTT
Mitral Valve Endocarditis on POCUS Echocardiogram 66 yo presents with petechiae to lower extremities. Pt had mitral
Pt had mitral valve ... narrow down all the DDX ... Echocardiogram #clinical ... cardiology #a4c #plax
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 Mixing Study • Clotting tests can be abnormal due to either a clotting factor deficiency, or
be normal. 1:1 Mix ... PT and/or aPTT)
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