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Primary and Secondary Causes of Mitral Regurgitation Primary (organic) chronic mitral regurgitation: • Leaflet: Rheumatic fever, Infective
and Secondary Causes ... Primary (organic) chronic ... • Prosthetic valve ... annulus valve: ... Regurgitation #differential
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis Algorithm Neoplasm: • NHL • Hodgkin's lymphoma • Leukemia • Solid
Causes of Fever ... Origin (FUO) - Differential ... endocarditis • ... UnknownOrigin #FUO #Chronic ... #Differential #
Faget's Sign & Liebermeister's Rule Pulse-Temperature Dissociation EVERY 1 F RISE IN TEMPERATURE -> HR INCREASES 8-10 BPM INFECTIOUS
INCREASES 8-10 BPM INFECTIOUS ... • Viral Hemorrhagic ... limited predictive value ... the most likely infection ... help hone your differential
Fever Patterns - Differential Diagnosis Framework Continuous Fever: Temp > 38°C with only 1 degree fluctuation in 24
Differential Diagnosis ... Acute bacterial endocarditis ... • Infective endocarditis ... Causes: • Still's ... #Patterns #Differential
Causes of Severe Aortic Regurgitation - Differential Diagnosis Acute: • Leaflet: Traumatic Rupture, Acute Infective Endocarditis, Acute
Causes of Severe ... Regurgitation - Differential ... Acute Prosthetic Valve ... Injury to Root Chronic ... , Rheumatic Fever
Causes of Thrombocytopenia - Differential Diagnosis Framework Decreased Production: - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... - Differential ... infiltration: malignancy, infection ... - Mechanical: valve ... replacement, endocarditis
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
Involves aortic and mitral ... night sweats, fever ... Septic Emboli Cause ... Marantic (NTBE) Differential ... Treat underlying cause
Causes of mitral stenosis Rheumatic heart disease - Most common cause worldwide. Commissural fusion, thick MV leaflets
Causes of mitral ... Age-related changes, chronic ... disease Infective endocarditis ... atrial myxoma)/ball valve ... #diagnosis #differential
Bradycardia - Differential Diagnosis Framework BRADI Mnemonic • BRASH/Hyperkalemia • Reduced oxygen/Glucose/Temp • ACS • Drugs •
Bradycardia - Differential ... Drugs • ICP / Infections ... Endocarditis + ... • Post cardiac/Valve ... #diagnosis #causes
Causes of Neutrophilia - Increased Neutrophils - Differential Diagnosis Algorithm Infection • Bacterial • Abscess • Viral Medications
Causes of Neutrophilia ... Diagnosis Algorithm Infection ... • Abscess • Viral ... Myeloproliferative Disorder • Chronic ... #Hematology
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