15 results
Primary and Secondary Causes of Mitral Regurgitation
Primary (organic) chronic mitral regurgitation:
 • Leaflet: Rheumatic fever, Infective
and Secondary Causes ... cushion defects), Systemic ... inflammation (SLE ... annulus valve: ... Regurgitation #differential
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Lupus (SLE) General ... : Fever (50%), Depression ... , Aortic valve lesions ... Abdominal pain ... #SLE #systemic
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Associated with Joint Pain ... Subacute bacterial endocarditis ... - Bacterial endocarditis ... conditions #joint #pain ... #differential #
Causes of mitral stenosis
Rheumatic heart disease
 - Most common cause worldwide. Commissural fusion, thick MV leaflets
Causes of mitral ... Secondary to systemic ... leaflets/chordae) - SLE ... atrial myxoma)/ball valve ... #diagnosis #differential
Causes of Severe Aortic Regurgitation - Differential Diagnosis
Acute:
 • Leaflet: Traumatic Rupture, Acute Infective Endocarditis, Acute
Causes of Severe ... Acute Prosthetic Valve ... , Rheumatic Fever ... Inflammatory: Lupus ... Degenerative: Systemic
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
Involves aortic and mitral ... • Autoimmune (SLE ... night sweats, fever ... Septic Emboli Cause ... Marantic (NTBE) Differential
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
and fingers, or pain ... the face (many differential ... ; sometimes « viral ... 9) Unexplained fever ... #clues #system
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Arthritis: • Joint pain ... • Libman-Sacks endocarditis ... Cytopenias • Cardiac valve ... #Systemic #Lupus
Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
and Differential ... involves aortic and mitral ... • Autoimmune (SLE ... night sweats, fever ... #Endocarditis #Differential
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Red Flags: • Fever ... lesions • Severe pain ... Schonlein Purpura - Endocarditis ... Autoimmune Vasculitis (lupus