14 results
Primary and Secondary Causes of Mitral Regurgitation
Primary (organic) chronic mitral regurgitation:
 • Leaflet: Rheumatic fever, Infective
Leaflet: Rheumatic fever ... • Prosthetic valve ... annulus valve: ... cardiomyopathy - VA Joint ... #differential #diagnosis
Causes of Severe Aortic Regurgitation - Differential Diagnosis
Acute:
 • Leaflet: Traumatic Rupture, Acute Infective Endocarditis, Acute
- Differential ... Acute Prosthetic Valve ... , Rheumatic Fever ... Inflammatory: Lupus ... #Differential #
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Subacute bacterial endocarditis ... Cardiovascular system • Mitral ... regurgitation and ... - Bacterial endocarditis ... #pain #differential
Myositis and Myopathies
Polymyositis 
 • Progressive, symmetric muscle weakness 
 • Elevated CK, +Anti-Jo, +Anti-Mi2
Dermatomyositis
Rheumatica • Pain ... , Fever, No muscle ... Detectable HIV viral ... Diffuse muscle pain ... Myopathies #myopathy #differential
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Features of Systemic Lupus ... (SLE) General: Fever ... Pericarditis, Endocarditis ... , Aortic valve lesions ... Abdominal pain
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Pain - Diagnostic ... acute rheumatic fever ... spondyloarthropathies, lupus ... #Joint #Pain #MSK ... approach #workup #differential
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
Involves aortic and mitral ... regurgitation ... night sweats, fever ... Marantic (NTBE) Differential ... Persistent bacteremia/fevers
Causes of Primary and Functional Mitral Regurgitation (MR) 
Causes of primary mitral regurgitation
 - Rheumatic heart
Infective/marantic endocarditis ... valve - Secondary ... of coaptation point ... #Mitral #Regurgitation ... Primary #Functional #Differential
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Differential Diagnosis ... • Rheumatic fever ... Viral Infections ... • Bacterial endocarditis ... #pain #Differential
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
) Inflammatory joint ... pain (especially ... the face (many differential ... ; sometimes « viral ... 9) Unexplained fever