15 results
Primary and Secondary Causes of Mitral Regurgitation
Primary (organic) chronic mitral regurgitation:
 • Leaflet: Rheumatic fever, Infective
and Secondary Causes ... inflammation (SLE ... annulus valve: ... cardiomyopathy - VA Joint ... Regurgitation #differential
Bradycardia - Differential Diagnosis Framework

BRADI Mnemonic
 • BRASH/Hyperkalemia
 • Reduced oxygen/Glucose/Temp
 • ACS
 • Drugs
 •
Bradycardia - Differential ... Endocarditis + ... • Post cardiac/Valve ... Autoimmune: • SLE ... #diagnosis #causes
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Associated with Joint ... Subacute bacterial endocarditis ... Cardiovascular system • Mitral ... - Bacterial endocarditis ... #pain #differential
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis Algorithm
Neoplasm:
• NHL
• Hodgkin's lymphoma
• Leukemia
• Solid
Causes of Fever ... Origin (FUO) - Differential ... Autoimmune: • SLE ... • Infectious endocarditis ... #FUO #Chronic #Differential
Causes of mitral stenosis
Rheumatic heart disease
 - Most common cause worldwide. Commissural fusion, thick MV leaflets
Causes of mitral ... leaflets/chordae) - SLE ... disease Infective endocarditis ... atrial myxoma)/ball valve ... #diagnosis #differential
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
Involves aortic and mitral ... • Autoimmune (SLE ... night sweats, fever ... Marantic (NTBE) Differential ... Persistent bacteremia/fevers
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... - Differential ... - Autoimmune: SLE ... - Mechanical: valve ... replacement, endocarditis
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
acute rheumatic fever ... Like in this case ... • Acute = Viral ... Chronic = RA, SLE ... approach #workup #differential
Causes of Primary and Functional Mitral Regurgitation (MR) 
Causes of primary mitral regurgitation
 - Rheumatic heart
Causes of Primary ... Infective/marantic endocarditis ... valve - Secondary ... of coaptation point ... #Functional #Differential
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Pain - Arthritis Differential ... weeks) Can Be Caused ... • Rheumatic fever ... • Bacterial endocarditis ... arthritis • SLE