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rheumatology cardiology causes erythematosus pain regurgitation sle arthritis msk primary systemic algorithm aortic approach clues comparison conditions dermatology extrarticular functional
Primary and Secondary Causes of Mitral Regurgitation Primary (organic) chronic mitral regurgitation: • Leaflet: Rheumatic fever, Infective
• Prosthetic valve ... annulus valve: ... cardiomyopathy - VA Joint ... Regurgitation #differential ... #diagnosis #cardiology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... (SLE) General: Fever ... Pericarditis, Endocarditis ... , Aortic valve lesions ... signs #symptoms #diagnosis
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
, Fever, No muscle ... Detectable HIV viral ... uncommon 5-15% of lupus ... Myopathies #myopathy #differential ... #diagnosis #comparison
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Pain - Diagnostic ... acute rheumatic fever ... spondyloarthropathies, lupus ... • Acute = Viral ... approach #workup #differential
Causes of Severe Aortic Regurgitation - Differential Diagnosis Acute: • Leaflet: Traumatic Rupture, Acute Infective Endocarditis, Acute
Regurgitation - Differential ... Diagnosis Acute ... Acute Prosthetic Valve ... , Rheumatic Fever ... Inflammatory: Lupus
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Subacute bacterial endocarditis ... Cardiovascular system • Mitral ... - Bacterial endocarditis ... #pain #differential ... #diagnosis #rheumatology
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
Involves aortic and mitral ... night sweats, fever ... Marantic (NTBE) Differential ... Persistent bacteremia/fevers ... #Endocarditis #diagnosis
Top 10 situations when to think about lupus 1) Inflammatory joint pain (especially in the wrists and
) Inflammatory joint ... the face (many differential ... diagnoses, including ... ; sometimes « viral ... 9) Unexplained fever
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... permanent alopecia Differential ... Arthritis: • Joint ... • Libman-Sacks endocarditis ... Cytopenias • Cardiac valve
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Pain - Arthritis Differential ... Diagnosis Framework ... • Rheumatic fever ... • Bacterial endocarditis ... #Diagnosis #MSK
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