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Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Statins - ETOH - Infection ... UA positive for blood ... Cast formation: ... hyperkalemia or ATN ... causes #treatment #nephrology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Kidney Injury (AKI ... ) - Differential ... C3/C4, Other • ATN ... AIN: Medication, Infection ... #Diagnosis #nephrology
Acute Kidney Injury - Differential Diagnosis Framework
PRERENAL:
 - Intrarenal vasoconstriction-hemodynamically mediated
 - Systemic vasodilation
 - Volume
Kidney Injury - Differential ... Glomerular (red blood ... eosinophils/white blood ... Kidney #Injury #AKI ... #Differential #
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
Kidney Injury (AKI ... Light chain (LC) cast ... Cisplatin • ATN ... Cancer #Oncology #Differential ... Classification #Nephrology
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm
Acute Kidney Injury (AKI) - Acute increase
) - Differential ... Epithelial cell casts ... Obstruction • Cast ... allopurinol, PPI) • Infections ... #KidneyInjury #Nephrology
Urine Microscopy - Casts
Acellular Casts
 • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Acellular Casts ... tubular necrosis (ATN ... can be either infectious ... or non-infectious ... Urine #Microscopy #nephrology
Common causes of Acute Kidney Injury AKI - Differential Diagnosis
HEMODYNAMIC
 • Cardiac failure: Impaired forward flow,
Kidney Injury AKI ... - Differential ... Post-infectious ... Injury/Necrosis (ATN ... #Diagnosis #nephrology
Guide to Acute Kidney Injury (AKI)

What to ask/look for: 
 - HPI, PMH, full ROS
Kidney Injury (AKI ... Liano 1996) - ATN ... CKD— 13% (mostly ATN ... #Nephrology #Diagnosis ... Algorithm #Causes #Differential
Urinary Casts and Disease Associations
Hyaline - May be nonspecific; seen in normal individuals or during severe
disease Red blood ... Glomerulonephritis White blood ... Urinary tract infections ... edgarvlermamd - Nephrology ... #Differential #
Algorithmic Approach to the Patient with Azotemia

#Azotemia #AKI #Nephrology #Diagnosis #Differential #Algorithm #Management
#Azotemia #AKI ... #Nephrology #Diagnosis ... #Differential # ... Algorithm #Management