19 results
I’M DAMN SHARP - Lupus Diagnosis Mnemonic
I  	 Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid)
M 	 Malar Rash
D
SHARP - Lupus Diagnosis ... Discoid Rash A Antinuclear ... Antibody (ANA) ... erythematosus #rheumatology ... #diagnosis #mnemonic
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
ANA (Antinuclear ... Antibody) and ANCA ... #Antinuclear #Antibody ... Antineutrophil #antibodies #diagnosis ... #rheumatology #
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Antinuclear Antibody ... • Reticular/AMA ... #Antinuclear #Antibody ... #differential #diagnosis ... #rheumatology
Antinuclear Antibody Testing Cytoplasmic Patterns
Reticular/AMA: 
 • PBC, SSc, PBC/SSc OS, PBC/SjS OS
 • AMA
Speckled:
 •
Antinuclear Antibody ... PBC/SjS OS • AMA ... #Antinuclear #Antibody ... #differential #diagnosis ... #rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Antibody refers ... , Interstitial Pulmonary ... #patterns #rheumatology ... #diagnosis #differential
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Erythematosus - Summary Antinuclear ... (ANA) - 95% - Initial ... #SLE #Summary #diagnosis ... #rheumatology # ... management
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
ANCA vasculitis (AAV ... Auto-antibodies: ANCA antibody ... , Anti-GBM antibody ... FINDINGS: • AAV ... #management #treatment
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... erythematosus (SLE) - Antinuclear ... antibody (ANA) ... titer, ACE level, CXR ... #testing #Rheumatology
Antinuclear Antibody Testing - Nuclear Patterns
Homogeneous pattern: 
 • SLE, SSc, AIH, JIA
 • dsDNA, chromatin,
Antinuclear Antibody ... ARUPConsult @ARUPLabs #ANA ... #Antinuclear #Antibody ... #differential #diagnosis ... #rheumatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
5 or elevated Cr ... common • Imaging: CXR ... - pulmonary opacities ... • Diagnosis: ... #management #hematology