27 results
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Liver Enzymes (LFTs ... Liver Injury ... skeletal muscle and kidney ... Transaminitis #diagnosis ... #differential #hepatology
Liver Function Tests (LFTs) - Normal Values and Interpretation

Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
(LFTs) - Normal ... hepatocellular injury ... Function #Tests #LFTs ... Interpretation #diagnosis ... #hepatology
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
(LFTs) Elevation ... skeletal muscle, kidney ... #FunctionTest #LFTs ... Transaminitis #diagnosis ... #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs ... • Gilbert's syndrome ... #chemistry #diagnosis ... #differential #Hepatology ... transaminitis #LFTs
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver ... Injury Transaminase ... #Injury #hepatology ... #LFTs #transaminitis ... #differential #diagnosis
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... - Differential Diagnosis ... vein: Budd-chiari syndrome ... • Gilbert's syndrome ... #algorithm #hepatology
Indications for Albumin for Management of Cirrhosis
 • Large volume paracentesis (>5 liter) - 8g per
removed • Acute kidney ... injury (≥ 1B) - ... • Hepatorenal syndrome ... Management #Cirrhosis #treatment ... #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
months without treatment ... Circulation Failure Kidney ... Injury (DILI) ... Failure #Cirrhosis #Hepatology ... gastroenterology #management #diagnosis
Acute Kidney Injury - Classification
Prerenal:
 • Dehydration
 • Heart failure (a.k.a. cardiorenal syndrome)
 • Liver failure
Acute Kidney Injury ... a.k.a. cardiorenal syndrome ... ) • Liver failure ... a.k.a. hepatorenal syndrome ... #diagnosis #nephrology
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
Acute Kidney Injury ... malignancies Treatment ... cyclophosphamide) #Acute #Kidney ... #Differential #Diagnosis ... Classification #Nephrology