104 results
Hypercalcemia of Malignancy - Pathophysiology
PTH-mediated
 • Parathyroid cancer
 • Ectopic production: Small cell lung cancer, ovarian
intestinal calcium absorption ... and stimulates resorption ... Stimulate calcium reabsorption ... kidney, Stimulates resorption ... Differential #Diagnosis #algorithm
Hypophosphatemia - Differential Diagnosis Algorithm
 • Decreased intake/absorption: Starvation, Alcoholism, Malabsorption, Phosphate binder use
 • Redistribution/
Differential Diagnosis Algorithm ... Decreased intake/absorption ... Malabsorption, Phosphate ... Differential #Diagnosis #Algorithm ... causes #nephrology #phosphate
Hyperphosphatemia - Differential Diagnosis Algorithm
Transcellular Shift:
 • Rhabdomyolysis
 • Tumor Lysis
 • Metabolic or Respiratory Acidosis
Differential Diagnosis Algorithm ... Increased Intake / Absorption ... Hypervitaminosis D • Phosphate ... Supplementation • Phosphate ... Differential #Diagnosis #Algorithm
Hypophosphatemia - Differential Diagnosis Algorithm
Appropriately Low Kidney Phosphate Excretion:
 • Decreased GI Absorption: Chronic Diarrhea, Antacids,
Differential Diagnosis Algorithm ... Appropriately Low Kidney Phosphate ... • Decreased GI Absorption ... Diarrhea, Antacids, Phosphate ... Differential #Diagnosis #Algorithm
Workup for Hyperphosphatemia - Differential Diagnosis Framework
Rule out spurious hyperphosphatemia: paraproteinemia, hyperlipidemia, hemolysis, hyperbilirubinemia, liposomal amphotericin
heparin Acute Phosphate ... Exogenous: Excessive phosphate ... intake, Phosphate ... Increased Renal Phosphate ... Absorption:
Characteristics of Commonly Used Phosphate Binders 
Aluminum 
 - Potent and effective 
 - Useful for
Commonly Used Phosphate ... - No systemic absorption ... - Significant absorption ... amzn.to/34t5DgJ #Phosphate ... #Binders #Table
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Alkaline Phosphatase ... Differential Diagnosis Algorithm ... hydrolysis of organic phosphate ... growth) Alkaline phosphatase ... Differential #Diagnosis #Algorithm
Hypophosphatemia - Measurement of urine phosphate excretion - Differential Diagnosis Algorithm
 • GI loss
 • Redistribution
Measurement of urine phosphate ... Differential Diagnosis Algorithm ... urine #urinary #phosphate ... Differential #Diagnosis #Algorithm
Hypercalcemia - Differential Diagnosis Algorithm
Elevated PTH (High or normal):
 • Primary Hyperparathyroidism
 • Familial Hypocalciuric Hypercalcemia
Low
Differential Diagnosis Algorithm ... Miscellaneous - Bone Resorption ... - Calcium Reabsorption ... Differential #Diagnosis #Algorithm
Phosphate binders - quick reference chart of maximum daily dose. Most patients with CKD will require
Phosphate binders ... CKD will require phosphate ... since they are not able ... based on serum phosphate ... aluminum-based phosphate