261 results
Workup for Hyperphosphatemia - Differential Diagnosis Framework
Rule out spurious hyperphosphatemia: paraproteinemia, hyperlipidemia, hemolysis, hyperbilirubinemia, liposomal amphotericin
Hyperphosphatemia - Differential ... heparin Acute Phosphate ... intake, Phosphate ... Absorption: ... Hyperphosphatemia #Differential
Hypercalcemia of Malignancy - Pathophysiology
PTH-mediated
 • Parathyroid cancer
 • Ectopic production: Small cell lung cancer, ovarian
intestinal calcium absorption ... and stimulates resorption ... Stimulate calcium reabsorption ... kidney, Stimulates resorption ... Pathophysiology #Differential
Hypophosphatemia - Differential Diagnosis Algorithm
 • Decreased intake/absorption: Starvation, Alcoholism, Malabsorption, Phosphate binder use
 • Redistribution/
Hypophosphatemia - Differential ... Decreased intake/absorption ... Malabsorption, Phosphate ... Hypophosphatemia #Differential ... causes #nephrology #phosphate
Hyperphosphatemia - Differential Diagnosis Algorithm
Transcellular Shift:
 • Rhabdomyolysis
 • Tumor Lysis
 • Metabolic or Respiratory Acidosis
Hyperphosphatemia - Differential ... Increased Intake / Absorption ... Hypervitaminosis D • Phosphate ... Supplementation • Phosphate ... HighPhosphate #Differential
Hypophosphatemia - Differential Diagnosis Algorithm
Appropriately Low Kidney Phosphate Excretion:
 • Decreased GI Absorption: Chronic Diarrhea, Antacids,
Hypophosphatemia - Differential ... Appropriately Low Kidney Phosphate ... • Decreased GI Absorption ... Diarrhea, Antacids, Phosphate ... Hypophosphatemia #Differential
Workup for Hypophosphatemia - Differential Diagnosis Framework
Rule out spurious hypophosphatemia: paraproteinemia, acute leukemia
Measure Urine Fractional Excretion
Hypophosphatemia - Differential ... Fractional Excretion of Phosphate ... diarrhea, Poor absorption ... Hypophosphatemia #Differential ... Framework #Workup #phosphate
Characteristics of Commonly Used Phosphate Binders 
Aluminum 
 - Potent and effective 
 - Useful for
Commonly Used Phosphate ... - No systemic absorption ... - Significant absorption ... amzn.to/34t5DgJ #Phosphate ... #Binders #Table
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Alkaline Phosphatase ... ALP) Elevation - Differential ... hydrolysis of organic phosphate ... growth) Alkaline phosphatase ... ALP #Elevation #Differential
Hypophosphatemia - Measurement of urine phosphate excretion - Differential Diagnosis Algorithm
 • GI loss
 • Redistribution
Measurement of urine phosphate ... excretion - Differential ... urine #urinary #phosphate ... #excretion #Differential
Hypercalcemia - Differential Diagnosis Algorithm
Elevated PTH (High or normal):
 • Primary Hyperparathyroidism
 • Familial Hypocalciuric Hypercalcemia
Low
Hypercalcemia - Differential ... Miscellaneous - Bone Resorption ... - Calcium Reabsorption ... Hypercalcemia #Differential