1078 results
Pathways Involved in Protein and Amino Acid Metabolism in Chronic Kidney Disease. The tricarboxylic acid (TCA)
Protein and Amino Acid ... tricarboxylic acid ... metabolize amino acids ... products of amino acid ... #Pathophysiology
Hyperuricemia: Pathogenesis and Complications

 - Hypercalcemia (due to diseases like Sarcoidosis and Hyperparathyroidism) -> Accumulation of
to filter uric acid ... like lactic acid ... and keto-acids) ... secretion of uric acid ... Hyperuricemia #Pathophysiology
Gastric Acid Secretion - Pathophysiology
Chief cell - Pepsinogen
Parietal cell - Acid, Intrinsic factor
G cell - Gastrin
Inhibitors:
Gastric Acid Secretion ... - Pathophysiology ... Parietal cell - Acid ... Somatostatin Phases of acid ... #Secretion #Pathophysiology
Mechanism of Action of Bile Acid Sequestrants
Bile Acid Sequestrants → ↓ Hepatic Bile Acid Pool →
Action of Bile Acid ... Sequestrants Bile Acid ... ↓ Hepatic Bile Acid ... ↑ Hepatic Bile Acid ... sequestration #pathophysiology
Tumor lysis syndrome (TLS) - Pathophysiology:
→ Massive tumor cell lysis
→ Release of large amounts of K+,
syndrome (TLS) - Pathophysiology ... phosphate, and uric acid ... deposition of uric acid ... syndrome #TLS #Pathophysiology
Lactulose: Mechanism of Action in Hepatic Encephalopathy
Lactulose → ↑ Lactic Acid, Acetic Acid → ↓ pH
Lactulose → ↑ Lactic Acid ... , Acetic Acid → ... ammonia #hepatology #pathophysiology
Tranexamic Acid: Mechanism of Action
 - TXA is an anti-fibrinolytic
 - TXA is a synthetic analog
Tranexamic Acid: ... analog of the amino acid ... #Tranexamic #Acid ... #pathophysiology
Uric Acid Homeostasis
In the liver, purines are metabolized to uric acid. The last step in purine
Uric Acid Homeostasis ... metabolized to uric acid ... converts uric acid ... the daily uric acid ... Homeostasis #Gout #Pathophysiology
Gout: Pathogenesis and Clinical Findings
 - Conditions of rapid cell turnover: hemolysis, psoriasis, lymphoproliferative disorders
 -
ketones and lactic acid ... compete with uric acid ... -> Incr uric acid ... joints -> Uric acid ... Hyperuricemia #Pathophysiology
Arachidonic acid pathway and drugs which affect it.

#Pharmacology #Pathophysiology #ArachidonicAcid #Pathways #COX #Prostaglandins #Prostacyclins #Leukotrienes #Synthesis

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Arachidonic acid ... #Pharmacology #Pathophysiology