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management lupus differential erythematosus hematology vasculitis classification druginduced signs symptoms syndrome workup anca antibodies antibody antineutrophil antinuclear arteritis behcet bleeding
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... (SLE) - Diagnosis ... Workup: - ANA ... life-threatening • Treatment ... #rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
- Summary Antinuclear ... (ANA) - 95% - Initial ... severe disease Treatment ... #Summary #diagnosis ... #rheumatology #
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Workup: - ANA ... months to years) Systemic ... Workup: - ANA ... comparison #table #rheumatology ... #diagnosis #management
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... in drug-induced SLE ... Jcortesizaguirr #ANA ... Antineutrophil #antibodies #diagnosis ... #rheumatology #
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... - Differential Diagnosis ... ASA) • Renal Disease ... #Algorithm #Causes ... #Hematology
Top 10 situations when to think about lupus 1) Inflammatory joint pain (especially in the wrists and
pericarditis (search ANA ... pleurisy (search ANA ... cytopenia (search ANA ... #sle #clues #system ... erythematosus #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... Erythematosus (SLE ... autoantibodies that will cause ... Erythematosus #SLE ... CNS #neurology #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often causes arthritis ... • GCA: - Aorta ... LFT • ESR • ANA ... SLE) • Urinalysis ... #rheumatology #
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Cryoglobulinemia Summary ... activate the immune system ... • They can cause ... Cryoglobulins Cause ... classification #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Autoimmune diseases: SLE ... Drugs, Unknown cause ... Treatment: • ... #management #treatment ... #summary #rheumatology
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