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management lupus differential erythematosus sle disease hematology syndrome algorithm ana antibodies antinuclear autoimmune table druginduced signs stills symptoms workup activetb
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in ... Rheumatology • ... Lupus (SLE): ANA ... • Scleroderma (Systemic ... diagnosis #associations
Systemic Sclerosis Associated Autoantibodies Anti-topoisomerase I (anti-Sc170): Diffuse skin disease, Pulmonary fibrosis Anti-centromere: Limited skin disease (~93-95%), Pulmonary
Systemic Sclerosis ... Associated Autoantibodies ... BCM_InternalMed #Systemic ... #Sclerosis #Autoantibodies ... #diagnosis #rheumatology
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Hemolytic Anemia 1) DIAGNOSE ... LDH • Anti-RBC autoantibodies ... FOR a cause → Systematic ... #management #treatment ... #rheumatology
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Autoantibodies and ... Disease Associations ANA ... Goodpasture's syndrome #Autoantibodies ... Associations #diseases #diagnosis ... #table #rheumatology
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
Retroperitoneum and aorta ... female, asian • Systemic ... conventional imaging (aorta ... serum lgE, no autoantibodies ... #rheumatology
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... • Homogeneous: Systemic ... Antinuclear #Antibodies #ANA ... #patterns #rheumatology ... #diagnosis #differential
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... the formation of autoantibodies ... permeability Diagnosis ... CNS #neurology #rheumatology ... #cerebritis #diagnosis
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Auto-Antibodies: - ANA ... Lupusreference #SLE #Systemic ... #autoantibodies ... #differential #rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... Antinuclear (ANA ... severe disease Treatment ... #SLE #Summary #diagnosis ... #rheumatology #
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
• Homogeneous: Systemic ... ) • Speckled: Systemic ... • Peripheral: Systemic ... #patterns #rheumatology ... #diagnosis #differential
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