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differential causes workup dermatology pruritus classification generalized hemolysis mcv pancytopenia secondary systemic thrombocytosis agglutinin alkaline alp chronic ckd cold deficiency
Hemolysis - Diagnostic Algorithm and Causes Increased red cell production: • Increased Reticulocytosis/polychromasia • Erythroid
Hemolysis - Diagnostic ... Algorithm and Causes ... Urobilinogen • + urinary ... #Hemolytic #Anemia ... Causes #Workup #Hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
- Differential Diagnosis ... Algorithm Decreased ... Reticulocytosis • Primary ... #Algorithm #Causes ... #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... anemia): ... usually IgM) (e.g. primary ... #differential #diagnosis ... #hematology #anemia
Hyperuricemia - Differential Diagnosis Algorithm Primary - Over-production • Increased turnover of nucleotides Primary
Algorithm Primary ... Leukemia (CML) - Hemolytic ... Anemia - Others ... Sarcoidosis • Hypercalcemia ... #Algorithm #endocrinology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach ... Diagnosis Framework ... , CKD • Hemolytic ... Non-megaloblastic: Liver disease ... #hematology
Hypercalcemia - Differential Diagnosis Algorithm Primary Hyperparathyroidism • Adenoma • Hyperplasia • MEN 1 and 2A Tertiary Hyperparathyroidism
Differential Diagnosis ... Algorithm Primary ... Granulomatous Disease ... #Differential #Diagnosis ... #Algorithm #Endocrinology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential Diagnosis ... Algorithm • Sickle ... #Diagnosis #Algorithm ... #workup #hematology
Hypercalcemia - Differential Diagnosis Algorithm Elevated PTH (High or normal): • Primary Hyperparathyroidism • Familial Hypocalciuric Hypercalcemia Low
Differential Diagnosis ... Algorithm Elevated ... or normal): • Primary ... Granulomatous Disease ... #endocrinology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
- Differential Diagnosis ... Algorithm Low ... • Bleeding • Hemolysis ... #Algorithm #Causes ... #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
- Differential Diagnosis ... Algorithm Spurious ... Myelogenous Leukemia • Primary ... disorders • Celiac disease ... Iron deficiency anemia
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