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differential hematology nephrology syndrome lupus summary druginduced erythematosus hemophagocytic hlh lymphohistiocytosis rhabdomyolysis signs symptoms systemic thrombocytopenia workup activation anesthesia anesthesiology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
, SCLE-DIL (terbinafine ... Discontinuation of causal ... Usual therapeutic management ... comparison #table #rheumatology ... #diagnosis #management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
) - Diagnosis and ... versus DIL • ... Positive in 60-80% of cases ... life-threatening • Treatment ... #rheumatology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Autoimmune • ITP • SLE ... • TTP/HUS • DIC ... #Algorithm #Causes ... #Hematology
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... - Differential Diagnosis ... Algorithm Persistent ... (MPA) • SLE ... #Algorithm #Causes
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... autoantibodies that will cause ... #CNS #neurology ... #rheumatology # ... #management #treatment
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Autoimmune diseases: SLE ... Drugs, Unknown cause ... Treatment: • ... #management #treatment ... #summary #rheumatology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
+ Bleeding Treatment ... Treat primary cause ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Cyclosporiasis - Diagnosis and Management Summary Pathogen: • Cyclospora cayetanensis • Foodborne, waterbone, and soil-transmitted. •
and Management ... • Anorexia, Nausea ... relevance of +PCR and -AFB ... #management #treatment ... #microbiology #
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
- Differential Diagnosis ... and Management ... if levels > 8mg/dL ... See updated ... #causes #treatment
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
- Differential Diagnosis ... Framework and Management ... Summary Causes ... #Management #causes ... #treatment #nephrology
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