13 results
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Suspect: Clinical ... and permanent alopecia ... lymphoproliferative syndrome Clinical ... • Nonscarring alopecia
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
likely it will be clinically ... erythematosus ( ... erythematosus ( ... erythematosus ( ... : Lupus (SLE), Systemic
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
Clinical Domains ... : Non-scarring alopecia ... • Arthritis domain ... least 2 joints • Neurologic ... Classification #Criteria #SLE
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... 40, F:M 9:1 • Clinical ... Photosensitivity, Alopecia ... Evolution: Chronic disease ... #Erythematosus
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus
Clinical and Immunologic Criteria

CLINICAL CRITERIA
 - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... Erythematosus Clinical ... - NON-SCARRING ALOPECIA ... SEROSITIS - RENAL - NEUROLOGIC ... #Lupus #Erythematosus
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Constitutional symptoms, Arthritis ... Erythematosus ( ... Photosensitivity, Alopecia ... Evolution: Chronic disease
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus ( ... SLE) Clinical ... Cerebrovascular Disease ... #Erythematosus ... #SLE #CNS #neurology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... (SLE) General: ... of hip (rare), Arthritis ... pain (20%) Renal disease ... #erythematosus #
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
develops on the background ... • Systemic lupus ... erythematosus ... erythematosus [ ... SLE], AOSD) • Infection
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
Pathogenesis and Clinical ... like rheumatoid arthritis ... RA) or systemic lupus ... erythematosus ( ... SLE) Signs / Symptoms