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Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... 40, F:M 9:1 • Clinical ... Photosensitivity, Alopecia ... • Immunologic Workup ... #lupus #Systemic
Initial Clinical and Laboratory Data Base for Defining Major Syndromes in Nephrology #Major #Syndromes #Nephrology #Diagnosis #Workup
Initial Clinical ... Defining Major Syndromes ... in Nephrology ... #Major #Syndromes ... #Workup #Differential
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... • Immunologic Workup ... months to years) Systemic ... Photosensitivity, Alopecia ... • Immunologic Workup
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation Syndrome ... develops on the background ... Clinical Presentation ... Fever is the main clinical ... erythematosus [SLE
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
- SLE Neurologic ... system • Entrapment ... Genitourinary system ... Musculoskeletal System ... Cardiovascular system
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... Criteria - Systemic ... Erythematosus Clinical ... - NON-SCARRING ALOPECIA ... SEROSITIS - RENAL - NEUROLOGIC
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Erythematosus Clinical ... : Non-scarring alopecia ... least 2 joints • Neurologic ... Classification #Criteria #SLE ... #Systemic #Lupus
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... of Systemic Lupus ... (SLE) General: ... Demyelinating syndromes ... Thrombocytopenia #Lupus #SLE
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... Erythematosus (SLE ... ) Clinical Manifestations ... Demyelinating Syndrome ... #CNS #neurology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
likely it will be clinically ... erythematosus (SLE ... erythematosus (SLE ... ), Sjogren's Syndrome ... Arthritis, Sjögren Syndrome
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