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diagnosis management differential causes oncology anemia hivaids opportunistic pharmacology prevention dermatology syndrome workup disorders hemolytic hemophagocytic hlh leukemia lymphohistiocytosis vasculitis
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Myelofibrosis Infectious ... disorders • Celiac disease ... effect following treatment ... following EtOH induced thrombocytopenia ... #Causes #Hematology
Thrombocytopenia - Differential Diagnosis Algorithm Decreased production: • Bone marrow suppression • Bone marrow failure • Bone
Thrombocytopenia ... Differential Diagnosis Algorithm ... infiltration • Infection ... MatthewHoMD #Thrombocytopenia ... #hematology #platelets
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Rebound effect from treatment ... Inflammatory Conditions: Rheumatologic ... Vasculitides, IBD, Celiac disease ... #hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Differential Diagnosis Algorithm ... Vasculitis • Infection ... Heart Valve) #Thrombocytopenia ... #Causes #Hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
inflammation • Thrombocytopenia ... SLE) - Viral infections ... APLS • Acute Infectious ... Differential #Diagnosis #hematology ... #rheumatology #
Von Willebrand Disease - Most common inherited bleeding disorder Clinical • Easy bruising •
Von Willebrand Disease ... platelet count (mild thrombocytopenia ... factor VIII) Treatment ... VonWillebrand #Disease ... #Diagnosis #Hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Differential Diagnosis Algorithm ... Thrombocytopenia ... ASA) • Renal Disease ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Differential Diagnosis Algorithm ... Schistocytes, thrombocytopenia ... inclusions - If infection ... Differential #Diagnosis #Algorithm ... #workup #hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
Differential Diagnosis Algorithm ... Infectious • ... • Gaucher's Disease ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
procedures - Infection ... PT, aPTT(liver disease ... bypass), LFT (liver disease ... or if a primary hematologic ... Causes #Workup #hematology
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