79 results
diagnosis differential management hematology lupus sle systemic erythematosus peds vasculitis algorithm causes pediatrics table ana antinuclear autoantibodies classification comparison thrombocytopenia
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... , Anti-Ro (SSA) ... and Anti-La (SSB ... Autoantibodies #Rheumatology ... #diagnosis #associations
I’M DAMN SHARP - Lupus Diagnosis Mnemonic I Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid) M Malar Rash D
SHARP - Lupus Diagnosis ... Immunoglobulins (Anti-dsDNA ... , Anti-Sm, Anti-phospholipid ... erythematosus #rheumatology ... #diagnosis #mnemonic
Systemic Sclerosis Associated Autoantibodies Anti-topoisomerase I (anti-Sc170): Diffuse skin disease, Pulmonary fibrosis Anti-centromere: Limited skin disease (~93-95%), Pulmonary
Autoantibodies Anti-topoisomerase ... I (anti-Sc170): ... Biliary Cirrhosis Anti-RNA ... Autoantibodies #diagnosis ... #rheumatology
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
- SLE Anti-histone ... - SLE Anti-SSA ... (Ro), Anti-SSB ( ... Associations #diseases #diagnosis ... #table #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Erythematosus - Diagnosis ... 5-10% - Anti- ... Differential Diagnosis ... Erythematosus #Diagnosis ... #differential #rheumatology
Inflammatory Myopathies Dermatomyositis • Onset: Subacute • Pattern: Proximal • CK: Up to 50X ULN • Autoantibodies:
, anti-Mi-2, anti-TIF ... Associated Features: Diagnosis ... over years, often diagnosed ... #differential #diagnosis ... #comparison #rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Anti-dsDNA (in 70% ... Anti-Sm (Smith) ... Anti-histone (in ... Antineutrophil #antibodies #diagnosis ... #rheumatology #
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
Elevated CK, +Anti-Jo ... Elevated CK, +Anti-Jo ... , +Anti-Mi2 Polymyalgia ... #differential #diagnosis ... #comparison #rheumatology
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
/full triad at diagnosis ... Around half of anti-SRP ... and anti-HMGCR ... Autoimmune #Myositis #diagnosis ... #rheumatology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Henoch-SchonIein Purpura Anti-GBM ... Limited to Kidney: Anti-GBM ... pulmonary involvement: Anti-GBM ... #differential #diagnosis ... #algorithm #rheumatology
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