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You’ll notice there is an IgM and an IgG core antibody. The presence of IgM anti-HBc
presence of IgM anti-HBc ... IgM anti-HBc is ... presence of IgG anti-HBc ... with HBV, IgG anti-HBc ... commonly run in the clinical
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Systemic lupus Anti-dsDNA ... when ANA+ without anti-dsDNA ... Anti-histone 60 ... neonatal lupus Anti ... -15% If SLE is clinically
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... ) - Anti-ENA ... cutaneous DIL), anti-Sm ... ) - Anti-histone ... 40, F:M 9:1 • Clinical
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
Pathogenesis and clinical ... Antinuclear Antibodies: Anti-Jo ... -1, Anti-OJ, Anti-Mi2 ... , Anti-SRP, Anti-EJ ... , Anti-PL12, Anti-PL7
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
40, F:M 9:1 • Clinical ... ANA > - Anti-ENA ... to 30% - Anti-dsDNA ... of cases - Anti-histone ... 60% - pANCA anti-MPO
Central Retinal Vein Occlusion (CRVO) Clinical: • Sudden, painless, monocular loss of vision • "Blood and
Occlusion (CRVO) Clinical ... Ophthalmology consult • Anti-vascular ... CRVO #Diagnosis #Clinical
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
ANTI-MDA5 DERMATOMYOSITIS ... auricular papules Clinical ... : up to 74% of anti-MDA5 ... Association of Anti-MDA5 ... Malignancy: • Anti-TIF1y
Idiopathic Thrombocytopenic Purpura Clinical: • Gingival • Menorrhagia • GI bleeding • Intracranial
Thrombocytopenic Purpura Clinical ... Corticosteroids • IVIG or anti-D
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Erythematosus Clinical ... IgG > 40 GPL or anti-ß2GPI ... antibodies domain: Anti-dsDNA ... antibody, Anti-Sm
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
Autoimmune Hepatitis Clinical ... Highly variable clinical ... ) (common, and Anti-LKM ... & Anti-ALC Abs ... mild laboratory, clinical
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