7652 results
Winged Scapula on Physical Exam

Common things being common just standard scapular winging, but this is more
thoracic /serratus ant ... #PhysicalExam #clinical ... #video #sports
Central Retinal Artery Occlusion: Pathogenesis and clinical findings
 • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
Pathogenesis and clinical ... and/or decreased anti-coagulation ... -> Cherry-red spot
Main types of autoimmune encephalitis in the ICU. 
Anti-NMDAR anti-N-methyl-d-aspartate receptor, ADEM acute disseminated encephalomyelitis, Anti-GFAP
Anti-NMDAR anti-N-methyl-d-aspartate ... anti-glial fibrillary ... anti-gamma aminobutyric ... anti-gamma aminobutyric ... anti-leucine-rich
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
screening test Anti-dsDNA ... disease activity Anti-Ro ... Sjogren syndrome Anti-UI-ribonucleoprotein ... overlap syndrome) Anti-Smith ... Hydroxychloroquine *Short
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
function over a short ... post-infectious GN Anti-Glomerular ... IF • Majority anti-neutrophil ... + • c-ANCA: anti-proteinase ... staining • p-ANCA: anti-myeloperioxidase
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
- SLE Anti-histone ... Drug-induced SLE Anti-Jo ... (AMA), Anti-sp100 ... - SLE Anti-SSA ... (Ro), Anti-SSB (
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Lupus (SLE): ANA (anti-nuclear ... , Anti-Ro (SSA) ... and Anti-La (SSB ... (SSA), Anti-La ... (SSB) • MCTD: Anti-UI
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
Anti-dsDNA (in 70% ... Anti-Sm (Smith) ... Anti-histone (in ... Anti-Ro/SSA ... Anti-La/SSB •
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Systemic lupus Anti-dsDNA ... when ANA+ without anti-dsDNA ... Anti-histone 60 ... neonatal lupus Anti ... -15% If SLE is clinically
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
60-70% - Anti-SSA ... 30-40% - Anti-SSB ... 5-10% - Anti- ... 5-15% - Anti-Ku ... 5-10% - Anti-PCNA