371 results
Dermatologic Extraintestinal Manifestations in IBD - IBD Algorithm

Erythema Nodosum
Pyoderma Gangrenosum
Metastatic Crohn's Disease
Sweet Syndrome
EBA

Dr. Wade Billings @wabillin

#Dermatologic
Dermatologic Extraintestinal ... Disease Sweet Syndrome ... @wabillin #Dermatologic ... gastroenterology #management #dermatology
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
- SLE Anti-histone ... Anticentromere - CREST syndrome ... - SLE Anti-SSA ... La) - Sjogren's syndrome ... Goodpasture's syndrome
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary Renal Syndrome ... Pulmonary Renal Syndromes ... Infection, Alport Syndrome ... ab, anti-GBM ab ... , ANA, C3, C4, anti-CCP
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
, Anti-Ro (SSA) ... and Anti-La (SSB ... Antiphospholipid Antibody Syndrome ... LAC) • Sjogren Syndrome ... : Anti-Ro (SSA),
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework
Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis
90%:
 -
Pulmonary Renal Syndromes ... Vasculitis - Anti-GBM ... Positive (ANCA + anti-GBM ... Antiphospholipid Syndrome ... differentiation syndrome
Aplastic Anemia and Bone Marrow Failure Syndromes with Pancytopenia

Fanconi Anemia
Acquired Aplastic Anemia
Dyskeratosis Congenita & Telemore Biology
Marrow Failure Syndromes ... Shwachman-Diamond Syndrome ... #Pancytopenia #Syndromes ... anemia #diagnosis #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Alloimmune • anti-HLA ... Non-lmmune: • HELLP Syndrome ... Algorithm #Causes #Hematology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
Anti-dsDNA (in 70% ... Anti-Sm (Smith) ... Anti-histone (in ... cases • Sjögren syndrome ... Anti-Ro/SSA
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
screening test Anti-dsDNA ... disease activity Anti-Ro ... block • Sjogren syndrome ... polymyositis overlap syndrome ... ) Anti-Smith -
ABO Blood Types and Transfusion Compatibility Table
A Blood Type:
 • RBC Antigens: A
 • Antibodies: Anti-B
• Antibodies: Anti-B ... • Antibodies: Anti-A ... • Antibodies: Anti-A ... , Anti-B - Dr ... Compatibility #Table #hematology