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dermatology clinical management diagnosis ucsdh skinrash rheumatology algorithm differential hepatology syndrome skin pharmacology vasculitis rash disease oncology table comparison lupus
I’M DAMN SHARP - Lupus Diagnosis Mnemonic I Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid) M Malar Rash D
Immunoglobulins (Anti-dsDNA ... , Anti-Sm, Anti-phospholipid ... Pleuritis) H Hematologic ... erythematosus #rheumatology
Hypereosinophilia and Hypereosinophilic Syndrome • Secondary Hypereosinophilic Syndrome • Clinically Relevant HES Variants • When to
suspect underlying hematologic ... Diagnosis and Treatment ... Syndrome #HES #Hematology
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... , Anti-Ro (SSA) ... and Anti-La (SSB ... (SSA), Anti-La ... Autoantibodies #Rheumatology
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
papules 30% w/ anti-synthetase ... Around half of anti-SRP ... and anti-HMGCR ... after 2 years of treatment ... Myositis #diagnosis #rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
screening test Anti-dsDNA ... disease activity Anti-Ro ... overlap syndrome) Anti-Smith ... severe disease Treatment ... Summary #diagnosis #rheumatology
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
- SLE Anti-histone ... (AMA), Anti-sp100 ... - SLE Anti-SSA ... (Ro), Anti-SSB ( ... diagnosis #table #rheumatology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Non malignant hematologic ... effect following treatment ... states • Non-hematologic ... Algorithm #Causes #Hematology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
ANA > - Anti-ENA ... to 30% - Anti-dsDNA ... 60% - pANCA anti-MPO ... life-threatening • Treatment ... Management #Summary #rheumatology
Systemic Sclerosis Associated Autoantibodies Anti-topoisomerase I (anti-Sc170): Diffuse skin disease, Pulmonary fibrosis Anti-centromere: Limited skin disease (~93-95%), Pulmonary
Autoantibodies Anti-topoisomerase ... I (anti-Sc170): ... Biliary Cirrhosis Anti-RNA ... skin fibrosis Anti-PM-Sc1 ... Autoantibodies #diagnosis #rheumatology
ABO Blood Types and Transfusion Compatibility Table A Blood Type: • RBC Antigens: A • Antibodies: Anti-B
• Antibodies: Anti-B ... • Antibodies: Anti-A ... • Antibodies: Anti-A ... , Anti-B - Dr ... Compatibility #Table #hematology
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