573 results
I’M DAMN SHARP - Lupus Diagnosis Mnemonic
I  	 Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid)
M 	 Malar Rash
D
Immunoglobulins (Anti-dsDNA ... , Anti-Sm, Anti-phospholipid ... Pleuritis) H Hematologic ... erythematosus #rheumatology
Mixing Study
 • Clotting tests can be abnormal due to either a clotting factor deficiency, or
Study • Clotting tests ... • Clotting tests ... order for the test ... Study #diagnosis #hematology ... pathophysiology #hematology
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... , Anti-Ro (SSA) ... and Anti-La (SSB ... (SSA), Anti-La ... Autoantibodies #Rheumatology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Initial screening test ... Anti-dsDNA - 50% ... disease activity Anti-Ro ... overlap syndrome) Anti-Smith ... Summary #diagnosis #rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
K), H. pylori test ... thyroid function test ... disease), HBsAg/anti-HBc ... or if a primary hematologic ... Causes #Workup #hematology
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
- SLE Anti-histone ... (AMA), Anti-sp100 ... - SLE Anti-SSA ... (Ro), Anti-SSB ( ... diagnosis #table #rheumatology
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Systemic lupus Anti-dsDNA ... Anti-histone 60 ... neonatal lupus Anti ... clinically suspected, tests ... erythematosus #diagnosis #rheumatology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Low Serum B12 - Anti-IF ... Low Serum B12 - Anti-IF ... Liver Function Tests ... Liver Function Tests ... Algorithm #Causes #Hematology
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus
Clinical and Immunologic Criteria

CLINICAL CRITERIA
 - ACUTE CUTANEOUS LUPUS
reference range - Anti-dsDNA ... tested by ELISA) - Anti-Sm ... determined by Positive test ... Direct Coombs’ test ... #Diagnosis #Rheumatology
Systemic Sclerosis Associated Autoantibodies
Anti-topoisomerase I (anti-Sc170): Diffuse skin disease, Pulmonary fibrosis
Anti-centromere: Limited skin disease (~93-95%), Pulmonary
Autoantibodies Anti-topoisomerase ... I (anti-Sc170): ... Biliary Cirrhosis Anti-RNA ... skin fibrosis Anti-PM-Sc1 ... Autoantibodies #diagnosis #rheumatology