2841 results
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
screening test Anti-dsDNA ... activity Anti-Ro ... Sjogren syndrome Anti-UI-ribonucleoprotein ... overlap syndrome) Anti-Smith ... Treatment: •
Persistent UC Symptoms Despite 5-ASA Therapies
 • Assess for Drug Adherence
 • Disease Activity Assessment (bloody
Drug Adherence • Disease ... Escalate Treatment ... Colitis Escalate Treatment ... - Anti-lntegrin ... - Anti-IL12
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
ANA > - Anti-ENA ... to 30% - Anti-dsDNA ... 60% - pANCA anti-MPO ... life-threatening • Treatment ... Evolution: Chronic disease
Causes of Iron Deficiency
 • Inadequate Intake: Vegetarian/vegan diet, Malnutrition
 • Increased Body Needs: Infants/preschoolers, Pregnancy,
Pregnancy, EPO treatment ... surgery, PPIs, Anti-H2 ... Edema, Celiac disease ... • Inflammatory Disease
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
) - Anti-ENA ... ) - Anti-histone ... constitutional symptoms • Treatment ... life-threatening • Treatment ... Evolution: Chronic disease
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Autoimmune diseases ... Adult-onset Still disease ... Unknown cause Treatment ... chemotherapy, anti-CD20 ... diagnosis #management #treatment
Non-HCV infectious mixed cryoglobulinemia vasculitis - Diagnosis, causes and management - French Vasculitis Study Group

< 5%
neuropathy Treatment ... - Specific anti-infectious ... the absence of anti-infectious ... with refractory disease
Esophageal Crohn's Disease Management Algorithm

Assess for Active Symptoms and for Stricturing/Fistulizing Disease
Stricturing DX:
 • Bx r/o
Esophageal Crohn's Disease ... Stricturing/Fistulizing Disease ... Endo • Anti-TNF ... Esophageal #Crohns #Disease ... Management #Algorithm #treatment
Chronic Obstructive Pulmonary Disease (COPD)
 • COPD Definition
 • Role of PFTs
 • COPD Classification and
Obstructive Pulmonary Disease ... Antimuscarinics) - Anti-inflammatory ... Obstructive #Pulmonary #Disease ... management #GOLD2022 #treatment
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Onset Still's Disease ... Treatment - Mild ... : NSAIDS Treatment ... , anti-lL6R, anti-ILI ... onset #Stills #disease