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diagnosis clinical management physicalexam neurology differential rheumatology ophthalmology algorithm msk ocular orthopedics pharmacology causes sports nephrology hematology test table disease
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
- SLE Anti-histone ... Anticentromere - CREST syndrome ... - SLE Anti-SSA ... La) - Sjogren's syndrome ... Goodpasture's syndrome
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
screening test Anti-dsDNA ... block • Sjogren syndrome ... polymyositis overlap syndrome ... ) Anti-Smith - ... severe disease Treatment
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary Renal Syndrome ... Pulmonary Renal Syndromes ... Infection, Alport Syndrome ... ab, anti-GBM ab ... , ANA, C3, C4, anti-CCP
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
, Anti-Ro (SSA) ... and Anti-La (SSB ... Antiphospholipid Antibody Syndrome ... LAC) • Sjogren Syndrome ... : Anti-Ro (SSA),
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis 90%: -
Pulmonary Renal Syndromes ... Vasculitis - Anti-GBM ... Positive (ANCA + anti-GBM ... Antiphospholipid Syndrome ... differentiation syndrome
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
papules 30% w/ anti-synthetase ... syndrome- Classic ... Around half of anti-SRP ... and anti-HMGCR ... after 2 years of treatment
Hyperthermia Syndromes Comparison Serotonin Syndrome - NMS - Malignant Hyperthermia - Malignant Catatonia Cause - Onset - Vitals
Hyperthermia Syndromes ... Comparison Serotonin Syndrome ... Mental Status - Treatment ... #Hyperthermia #Syndromes
Anti-infective stewardship, including tips for using anti-infectives wisely, criteria for stepdown from IV to PO dosage
Anti-infective stewardship ... tips for using anti-infectives ... conversion of IV to PO anti-infectives ... medications #table #treatment
Comparison of anti-diabetic or anti-hyperglycemic agents There are numerous anti-hyperglycemic agents available to manage Type 2 diabetes.
Comparison of anti-diabetic ... or anti-hyperglycemic ... There are numerous anti-hyperglycemic ... capability of anti-hyperglycemic ... endocrinology #treatment
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Anti-dsDNA (in 70% ... Anti-Sm (Smith) ... Anti-histone (in ... cases • Sjögren syndrome ... Anti-Ro/SSA
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