32 results
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Aliskiren) • Renin ... #hyperkalemia #differential ... #diagnosis #pathophysiology ... #pharmacology # ... potassium #medications
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
that Impair Renal Potassium ... ARBs Decreased Renin ... #Hyperkalemia #Pathophysiology ... #Pharmacology # ... Impaired #Potassium
Pathophysiology of the Renin-angiotensin-aldosterone system (RAAS) and inhibitors

#Pathophysiology #Pharmacology #RAAS #Renin #Angiotensin #Aldosterone #System #ACEInhibitors
Pathophysiology ... of the Renin-angiotensin-aldosterone ... inhibitors #Pathophysiology ... #Pharmacology # ... RAAS #Renin #Angiotensin
Hyperkalemia: Diagnostic algorithm
Decreased renal potassium excretion
 • Acute renal failure
 • Chronic renal failure
 • Drugs
Increased
Decreased renal potassium ... Drugs Increased potassium ... Diabetic Nephropathy Renin ... Normal, Renin High ... #differential
Here’s a review of the Renin-Angiotensin-Aldosterone system (RAAS)

This is a very common pathway that clinicians should
review of the Renin-Angiotensin-Aldosterone ... with excreting potassium ... will increase potassium ... ReninAngiotensinAldosteroneSystem #RAAS #Pharmacology ... #Renin #Angiotensin
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Hypokalemia - Differential ... #Hypokalemia #Differential ... Algorithm #causes #potassium ... #low #pathophysiology
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Digoxin Pharmacology ... and Pathophysiology ... the cell, serum potassium ... CaitEKulig #Digoxin #Pharmacology ... #Pathophysiology
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
treated with IV potassium ... Pressure: - ↑ Renin ... tumor - ↓ Renin ... diagnosis #Algorithm #differential ... #potassium #nephrology
Hyperkalemia Differential Diagnosis Algorithm
R/O Pseudo-hyperkalemia:
 • Possible Lab error! Alwavs Repeat Blood sample!
 • Leukocytosis, Thrombocytosis:
Hyperkalemia Differential ... #Hyperkalemia #Differential ... Algorithm #causes #potassium ... #high #pathophysiology
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Renovascular HTN, Renin ... #Hypokalemia #Differential ... Algorithm #causes #potassium