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diagnosis algorithm causes hypokalemia hyperkalemia low diuretics high management action alkalosis channelblockers druginduced drugs encephalopathy hypomagnesemia hypomg k metabolic nephrolithiasis
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
Hyperkalemia • Direct renin ... Aliskiren) • Renin ... #hyperkalemia #differential ... pathophysiology #pharmacology ... #potassium #medications
Diuretics sites of action on the nephron 1) Acetazolamide (carbonic anhydrase inhibitor) 2) Osmotic diuretics (e.g. mannitol) 3) Loop
Metolazone) 5) Potassium-sparing ... nephron #diuretics #pharmacology ... #nephrology #medications
Hyperkalemia: Diagnostic algorithm Decreased renal potassium excretion • Acute renal failure • Chronic renal failure • Drugs Increased
Decreased renal potassium ... Diabetic Nephropathy Renin ... Normal, Renin High ... Diagnosis #algorithm #nephrology ... #potassium #differential
Potassium Channel Blockers - Medications 1. Cardiovascular Drugs 2. Psychiatric drugs 3. Other drugs 4. Synthetic opioids: Levomethadyl 5. Opium
Potassium Channel ... Blockers - Medications ... ChannelBlockers #Medications ... #Differential # ... Diagnosis #Pharmacology
Summary of Diuretic Agents Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction CARBONIC ANHYDRASE
Chlorthalidone POTASSIUM-SPARING ... #Diuretics #Medications ... #Pharmacology # ... summary #table #nephrology
Hypokalemia - Differential Diagnosis Algorithm Transcellular Shift: • Alkalosis • ↑ beta-2 adrenergic simulation • Erythropoiesis
Hypokalemia - Differential ... Thyrotoxicosis Medications ... #Hypokalemia #Differential ... Diagnosis #Algorithm #nephrology ... #low #potassium
Hypokalemia - Differential Diagnosis Algorithm Extra-renal Losses: • Normal Acid-Base: Low intake • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Renovascular HTN, Renin ... #Hypokalemia #Differential ... Algorithm #causes #potassium ... #low #nephrology
Hypokalemia Evaluation Algorithm Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
treated with IV potassium ... Pressure: - ↑ Renin ... tumor - ↓ Renin ... diagnosis #Algorithm #differential ... #potassium #nephrology
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine Urine K+
the basis of the potassium-to-creatinine ... artery stenosis, Renin ... hypokalemia #urine #potassium ... #differential # ... algorithm #diagnosis #nephrology
Hypokalemia Differential Diagnosis Algorithm Hypertensive: • High Al, Low R - Primary aldosteronism • High Al, High
Hypokalemia Differential ... renovascular HT, Renin-secreting ... #Hypokalemia #Differential ... Diagnosis #Algorithm #nephrology ... #causes #low #potassium
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