83 results
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Differential Diagnosis Algorithm ... Primary Causes ... Liver Function Tests ... Myelodisplastic syndrome ... #causes
Mucous Membrane Disorder - Differential Diagnosis Algorithm
Erosions/Ulcers/Blisters
 - Primary Dermatologic Diseases
     •
Differential Diagnosis Algorithm ... Stevens-Johnson Syndrome ... necrolysis - Systemic ... Systemic lupus ... #causes
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Initial screening test ... Associated with skin ... block • Sjogren syndrome ... polymyositis overlap syndrome ... Summary #diagnosis #rheumatology
Vesiculobullous Skin Rash - Differential Diagnosis Algorithm
Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions
 - Inflammatory
Vesiculobullous Skin ... Rash - Differential ... Diagnosis Algorithm ... • Bullous systemic ... #causes
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... Demyelinating syndromes ... pain (20%) Renal disease
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
decades of life Causes ... and clinical associations ... trigger - Direct skin ... - Ice cube test ... Urticaria #diagnosis #rheumatology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
disease. ... sudden onset of a rash ... - Rash: multiple ... Causes: - Idiopathic ... , breast CA - Hematologic
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Clinical Presentation ... Fever is the main clinical ... Petechial or purpuric rash ... Liver function tests ... Diagnosis #Management #Hematology
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
Differential Diagnosis Algorithm ... arthritis - (Reiter’s syndrome ... arthritis - with the skin ... like “butterfly rash ... Differential #Diagnosis #Algorithm
Disorders of Pigmentations - Hypopigmentation and Hyperpigmentation - Differential Diagnosis Algorithm

HYPOPIGMENTATION
Diffuse Congenital - Generalized hypopigmentation of
of hair, eyes, skin ... sclerosis (white "ash ... • Addison's disease ... McCune Albright syndrome ... #causes