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Pulmonary Renal Syndrome: Investigations and Management

#Pulmonary #Renal #Syndrome #Diagnosis #Workup #Management
Pulmonary Renal ... Syndrome: Investigations ... and Management ... #Pulmonary #Renal ... #Workup #Management
Localization of Renal Tubular Defects
Fanconi Syndrome: Proximal tubule
Bartter Syndrome: Thick ascending loop of Henle
Gitelman Syndrome: Distal
Localization of Renal ... Defects Fanconi Syndrome ... tubule Bartter Syndrome ... Nephron #Defects #Pathophysiology ... #Nephrology
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary Renal ... Syndrome Definition ... Renal Syndromes ... #Renal #Syndrome ... differential #diagnosis #nephrology
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework
Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis
90%:
 -
Pulmonary Renal ... Vasculitis - Normal ... Levels: Scleroderma Renal ... Kumfer @AnnKumfer #Pulmonary ... #Renal #Syndromes
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Algorithm Extra-renal ... Losses: • Normal ... loss (Diarrhea) Renal ... , Gitelman syndrom ... potassium #low #nephrology
Mechanisms of nephron damage in cardiorenal syndrome
 • Increased renal interstitial pressure
 • Hypoperfusion
 • Reduced
in cardiorenal syndrome ... • Increased renal ... #cardiorenal #syndrome ... #Mechanisms #pathophysiology ... #nephrology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
investigations abnormal ... , HIV serology, ... renal biopsy • ... Abdominal compartment syndrome ... syndrome: troponin
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Diagnosis Algorithm Syndrome ... Pain/Post-op • Neurologic ... • Drugs • Pulmonary ... GI losses • Renal ... • Nephrotic syndrome
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Diagnosis Algorithm Syndrome ... Pain/Post-op • Neurologic ... • Drugs • Pulmonary ... GI losses • Renal ... • Nephrotic syndrome
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Pulmonary Renal ... Syndromes - OnePager ... Renal Syndromes ... #Renal #Syndromes ... differential #diagnosis #management