15 results
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... and Management ... , oral ulcers, Lupus ... - CRP: Usually normal ... life-threatening • Treatment
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... Disease, PRES Pathophysiology ... Erythematosus #SLE ... cerebritis #diagnosis #management ... #treatment
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
CRP - Usually normal ... constitutional symptoms • Treatment ... life-threatening • Treatment ... Usual therapeutic management ... rheumatology #diagnosis #management
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
Measurement in SLE ... 200ng/mL Best indications ... #rheumatology #pharmacology ... #levels #lupus ... #management
Algorithm for the Treatment of Membranous Lupus Nephritis
Sub-nephrotic-range proteinuria (<3.5g/d, normal serum albumin) and Preserved kidney
Algorithm for the Treatment ... of Membranous Lupus ... proteinuria (<3.5g/d, normal ... treat non-renal SLE ... #management #nephrology
Atopic Dermatitis - Topical Treatment Options 
First Line: Topical Corticosteroids 
  - High Potency: Betamethasone
Dermatitis - Topical Treatment ... After non-pharmacologic ... than roflumilast (see ... #Medications #Pharmacology ... #Dermatology #Management
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
DPP4 Inhibitors - Normal ... If you see a patient ... very tolerable medication ... Renal #Dosing #Pharmacology ... #Management #Diabetes
Drug Induced Systemic Lupus Erythematosus
> 100 drugs have been associated with drug-induced SLE
High risk (>5%):
 •
Induced Systemic Lupus ... with drug-induced SLE ... for 1 year of treatment ... Erythematosus #medications ... #drugs #pharmacology
Medication Protocol for Management of Delirium in Older Adults - Always start low and go slow
Olanzapine
Medication Protocol ... for Management ... Olanzapine 5 mg PO/SL ... Protocol #Geriatrics #Treatment ... #Pharmacology #
Pharmacologic Options for Hypercalcemia Associated with Cancer
Rehydration with NS followed by loop diuretics
 • IV normal
Pharmacologic Options ... diuretics • IV normal ... tube First-line medications ... #management #drugs ... #treatment #pharmacology