25 results
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
Acute Rheumatic Fever ... inflammation • Fever ... • Arthralgia ... pathophysiology #diagnosis #signs
Adult Onset Still's Disease - Yamaguchi Criteria
Major criteria:
 - Fever >= 39C lasting >= 1 weeks
criteria: - Fever ... = 1 weeks - Arthralgia ... with concomitant fever ... #Major #Minor #Rheumatology
Lyme Disease: Early and Late Clinical manifestations
Stage 1. Localized
 • EM appears 7-14 days at the
Fatigue, myalgia, arthralgia ... , headache, fever ... Disease #diagnosis #signs
Systemic Lupus Erythematosus (SLE) - Typical Signs/Symptoms
Alopecia, Fever, Malar rash, Photosensitivity, Adenopathies, Lupus pneumonia, Pleurisy, Pancreatitis,
SLE) - Typical Signs ... Symptoms Alopecia, Fever ... nephritis, Cytopenia, Arthralgia ... Erythematosus #SLE #Signs ... Symptoms #diagnosis #rheumatology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad: Fever ... , Arthralgia/arthritis ... management #treatment #rheumatology
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
- Fever spikes ... • Arthritis, arthralgias ... Fever of at least ... Arthralgias or arthritis ... AOSD #diagnosis #rheumatology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Illness Script Signs ... if neutropenic fever ... management #treatment #hematology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
(SLE) General: Fever ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Primary Adrenal Insufficiency
Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
vomiting • Fatigue Signs ... • Low-grade fever ... Back pain • Arthralgia ... Cortisol Deficiency: Signs ... Reduced libido • Signs
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
chest (in a V-sign ... Inverse Gottron’s sign ... Dermatomyositis • Fever ... 20% of cases • Arthralgia ... Dermatomyositis #rheumatology